SCHEMBL22117412

SCHEMBL22117412

CC(C)(C)OC(=O)NC(Cc1ccccc1)C(=O)NC(CCCCNC(=O)O)C(N)=O

nearest known ligand 0.59

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ REN P00797 3/20 0.59
▸ CTSS P25774 3/20 0.58
▸ CTSL P07711 2/20 0.58
▸ CTSK P43235 2/20 0.58
▸ CTSB P07858 1/20 0.58
▸ CCKBR P32239 4/20 0.55
▸ AKT1 P31749 1/20 0.54
▸ PTPN1 P18031 2/20 0.53
▸ PTPN2 P17706 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22117411 1.00 REN (0.59) RENCTSSCTSLCTSKCTSB
SCHEMBL22117422 0.94 REN (0.54) RENCTSSCTSLCTSKCTSB
SCHEMBL22117421 0.94 REN (0.54) RENCTSSCTSLCTSKCTSB
SCHEMBL17073778 0.91 CTSL (0.64) RENCTSSCTSLCTSKCTSB
SCHEMBL20653746 0.89 CTSL (0.67) RENCTSSCTSLCTSKCTSB
SCHEMBL22117409 0.88 REN (0.48) RENCTSSCTSLCTSKCTSB
SCHEMBL22117410 0.88 REN (0.48) RENCTSSCTSLCTSKCTSB
SCHEMBL16869898 0.87 MAPT (0.59) RENCTSLCCKBR
SCHEMBL11050511 0.86 REN (0.75) RENCTSSCTSLCTSKCTSB
SCHEMBL22962389 0.86 REN (0.75) RENCTSSCTSLCTSKCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3898652-A1 MITOCHONDRIA-TARGETING PEPTIDES Stealth Biotherapeutics Corp (MC) 2021-10-27 — — EP disclosed
WO-2020131282-A1 MITOCHONDRIA-TARGETING PEPTIDES STEALTH BIOTHERAPEUTICS CORP. (MC) 2020-06-25 — — WO disclosed
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