SCHEMBL22117409

CC(C)(C)OC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c(F)c(F)c(F)c(F)c1F)C(=O)N[C@@H](CCCCNC(=O)O)C(N)=O

nearest known ligand 0.51

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	REN	P00797	3/20	0.48

▸	CCKBR	P32239	2/20	0.48

▸	NPY4R	P50391	4/20	0.48

▸	NPY1R	P25929	2/20	0.46

▸	NPY2R	P49146	2/20	0.46

▸	NPY5R	Q15761	2/20	0.46

▸	CTSS	P25774	3/20	0.46

▸	CTSL	P07711	1/20	0.46

▸	CTSB	P07858	1/20	0.46

▸	CTSK	P43235	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL22117410	1.00	REN (0.48)	RENCCKBRNPY4RNPY1RNPY2R
SCHEMBL22117421	0.94	REN (0.54)	RENCCKBRNPY4RNPY1RNPY2R
SCHEMBL22117422	0.94	REN (0.54)	RENCCKBRNPY4RNPY1RNPY2R
SCHEMBL22117577	0.94	CTSS (0.52)	CCKBRNPY4RNPY1RNPY2RNPY5R
SCHEMBL22117580	0.94	CTSS (0.52)	CCKBRNPY4RNPY1RNPY2RNPY5R
SCHEMBL31679022	0.93	CTSL (0.51)	RENCCKBRNPY4RNPY1RNPY2R
SCHEMBL28639436	0.92	REN (0.46)	RENCCKBRNPY4RNPY1RNPY2R
SCHEMBL28639434	0.92	REN (0.46)	RENCCKBRNPY4RNPY1RNPY2R
SCHEMBL31679016	0.91	KLK7 (0.50)	CCKBRNPY4RCTSSCTSL
SCHEMBL22117412	0.88	REN (0.59)	RENCCKBRCTSSCTSLCTSB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-3898652-A1	MITOCHONDRIA-TARGETING PEPTIDES	Stealth Biotherapeutics Corp (MC)	2021-10-27	—	—	EP	disclosed
WO-2020131282-A1	MITOCHONDRIA-TARGETING PEPTIDES	STEALTH BIOTHERAPEUTICS CORP. (MC)	2020-06-25	—	—	WO	disclosed