Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25377959 | 0.76 | — | — | |
| SCHEMBL25377955 | 0.76 | — | — | |
| SCHEMBL19813049 | 0.73 | RXFP1 (0.35) | SMN1; SMN2RXFP1 | |
| SCHEMBL288906 | 0.72 | FAAH (0.37) | MEN1KMT2A | |
| SCHEMBL15663456 | 0.72 | FAAH (0.37) | MEN1KMT2A | |
| SCHEMBL11006249 | 0.72 | RXFP1 (0.30) | RXFP1 | |
| SCHEMBL3154599 | 0.72 | FAAH (0.37) | MEN1KMT2A | |
| SCHEMBL16761492 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL14779910 | 0.71 | ALDH1A1 (0.32) | — | |
| SCHEMBL4904256 | 0.71 | ALDH1A1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132004-A1 | BET INHIBITORS FOR MODULATING DUX4 EXPRESSION IN FSHD | SAINT LOUIS UNIVERSITY (US) | 2020-06-25 | — | — | WO | disclosed |