SCHEMBL288906

SCHEMBL288906

CON(C)C(=O)C(C)NC(=O)O

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.37
CTSL P07711 1/20 0.30
CTSB P07858 1/20 0.30
CTSS P25774 1/20 0.30
CTSK P43235 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
PKM P14618 1/20 0.30
RAB9A P51151 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3154599 1.00 FAAH (0.37) FAAHCTSLCTSBCTSSCTSK
SCHEMBL15663456 1.00 FAAH (0.37) FAAHCTSLCTSBCTSSCTSK
Ammonia Solution, Strong SCHEMBL15303247 0.98 FAAH (0.36) FAAH
SCHEMBL12629160 0.83 FAAH (0.37) FAAHCTSLCTSBCTSSCTSK
SCHEMBL10980085 0.83 FAAH (0.37) FAAHCTSLCTSBCTSSCTSK
SCHEMBL16234969 0.80 FAAH (0.35) FAAH
SCHEMBL4480182 0.80 FAAH (0.35) FAAHCTSLCTSBCTSSCTSK
SCHEMBL19746826 0.80 FAAH (0.35) FAAHCTSLCTSBCTSSCTSK
SCHEMBL22030293 0.80 CTSL (0.37) FAAHCTSLCTSBCTSSCTSK
SCHEMBL10988574 0.80 CTSL (0.37) FAAHCTSLCTSBCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240199604-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-20 US disclosed
US-20240201205-A1 METHOD FOR DETECTING NEUROLOGICAL DISEASES USING SUPRAMOLECULE POLYMER THERAPEUTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-20 US disclosed
US-20240197682-A1 METHOD FOR TREATING NEUROLOGICAL DISEASES USING SUPRAMOLECULE POLYMER THERAPEUTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-06-20 US disclosed
WO-2024059845-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-03-21 WO disclosed
US-20240050437-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF TWELVE THERAPEUTICS, INC. 2024-02-15 US disclosed
CN-117529476-A Preparation of substituted 1, 2-diamino heterocyclic derivatives and their use as medicaments 亚飞络思制药公司 2024-02-06 CN disclosed
EP-3402777-B1 OXAZOLIDINONES AS TARO INHIBITORS MERCK SHARP & DOHME (US) 2023-12-13 EP disclosed
US-11738010-B2 Oxazolidinones as TarO inhibitors MERCK SHARP & DOHME CORP. (US) 2023-08-29 US disclosed
US-20230138851-A1 NOVEL ALKYNE DERIVATIVES CARNA BIOSCIENCES, INC. (JP) 2023-05-04 US disclosed
US-11623927-B2 Substituted [1,2,4]triazolo[1,5-a]pyrimidines for stabilizing microtubules THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) 2023-04-11 US disclosed
US-20110263607-A1 ALPHA HELIX MIMETICS IN THE TREATMENT OF CANCER PRISM BIOLAB CORPORATION (JP) 2011-10-27 US disclosed
EP-2346871-A1 ALPHA HELIX MIMETICS IN THE TREATMENT OF CANCER PRISM BioLab Corporation (JP) 2011-07-27 EP disclosed
US-20110152296-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES AMGEN INC. (US) 2011-06-23 US disclosed
US-20110092459-A1 ALPHA HELIX MIMETICS AND METHODS RELATING THERETO PRISM BIOLAB CORPORATION (JP) 2011-04-21 US disclosed
EP-2303887-A1 ALPHA HELIX MIMETICS AND METHODS RELATING THERETO Prism Biolab Corporation (JP) 2011-04-06 EP disclosed
US-20100331306-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES AMGEN INC. (US) 2010-12-30 US disclosed
WO-2010128685-A1 ALPHA HELIX MIMETICS AND METHODS RELATING THERETO PRISM BIOLAB CORPORATION (JP) 2010-11-11 WO disclosed
WO-2010044485-A1 ALPHA HELIX MIMETICS IN THE TREATMENT OF CANCER PRISM BIOLAB CORPORATION (JP) 2010-04-22 WO disclosed
US-20100076010-A1 ALPHA 1A-ADRENOCEPTOR ANTAGONISTS CONCERT PHARMACEUTICALS, INC. 2010-03-25 US disclosed
WO-2009148192-A1 ALPHA HELIX MIMETICS AND METHODS RELATING THERETO PRISM BIOLAB CORPORATION (JP) 2009-12-10 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240199604-A1 SUPRAMOLECULAR POLYMER THERAPEUTICS AND DIAGNOSTICS MAPT, HTT, PSEN1 FAAH 3696/4885CTSL 1598/4885CTSB 1443/4885
US-20240050437-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF PIK3CA, PIK3CD, PIK3CB FAAH 2876/4885CTSL 2965/4885CTSB 1127/4885
US-20100076010-A1 ALPHA 1A-ADRENOCEPTOR ANTAGONISTS ADRA1D, ADRA1A, ADRB1 FAAH 1071/4885CTSL 3480/4885CTSB 3795/4885
US-11623927-B2 Substituted [1,2,4]triazolo[1,5-a]pyrimidines for stabilizing microtubules TUBB1, TUBA1B, TUBA1C FAAH 4221/4885CTSL 4683/4885CTSB 4096/4885
US-20100331306-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES MCL1, BCL9, MALT1 FAAH 1257/4885CTSL 2010/4885CTSB 1017/4885
US-20110152296-A1 HETEROCYCLIC COMPOUNDS AND THEIR USES MCL1, BCL9, MALT1 FAAH 1251/4885CTSL 2002/4885CTSB 1014/4885
US-20110092459-A1 ALPHA HELIX MIMETICS AND METHODS RELATING THERETO COL1A1, PLOD3, THPO FAAH 3219/4885CTSL 717/4885CTSB 1266/4885
US-20110263607-A1 ALPHA HELIX MIMETICS IN THE TREATMENT OF CANCER COL1A1, HDGF, HCCS FAAH 4052/4885CTSL 1385/4885CTSB 1921/4885
US-20230138851-A1 NOVEL ALKYNE DERIVATIVES DYRK1B, DYRK3, DYRK2 FAAH 3416/4885CTSL 3146/4885CTSB 2111/4885
US-20240197682-A1 METHOD FOR TREATING NEUROLOGICAL DISEASES USING SUPRAMOLECULE POLYMER THERAPEUTICS PRNP, PSEN1, SNCA FAAH 4189/4885CTSL 2492/4885CTSB 2287/4885
US-11738010-B2 Oxazolidinones as TarO inhibitors OXA1L, DDO, ALPI FAAH 4546/4885CTSL 1442/4885CTSB 1253/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.