Sugi Predict

Sugi Predict / Compounds / SCHEMBL221182

SCHEMBL221182

SCHEMBL221182

CC(C)(C)OC(=O)N/C=C/N

nearest known ligand 0.37

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MAPK10 P53779 1/20 0.37
▸ CA1 P00915 2/20 0.37
▸ CA7 P43166 2/20 0.37
▸ CA12 O43570 2/20 0.37
▸ CA14 Q9ULX7 2/20 0.37
▸ TDP1 Q9NUW8 1/20 0.36
▸ CTSK P43235 5/20 0.36
▸ DGAT1 O75907 1/20 0.35
▸ CA2 P00918 2/20 0.35
▸ MAOA P21397 1/20 0.35
▸ MAOB P27338 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ MEN1 O00255 1/20 0.34
▸ GAA P10253 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ MIF P14174 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17574717 1.00 MAPK10 (0.37) MAPK10CA1CA7CA12CA14
SCHEMBL8035972 1.00 MAPK10 (0.37) MAPK10CA1CA7CA12CA14
Hydrochloric Acid SCHEMBL2014400 0.98 MAPK10 (0.36) MAPK10CA1CA7CA12CA14
Acrylamide SCHEMBL23457730 0.89 ALDH1A1 (0.38) MAPK10CA1CA7CA12CA14
SCHEMBL15096829 0.86 MAPK10 (0.41) MAPK10CA1CA7CA12CA14
SCHEMBL12571335 0.86 MAPK10 (0.41) MAPK10CA1CA7CA12CA14
SCHEMBL8603435 0.84 CTSK (0.43) MAPK10CA1CA7CA12CA14
SCHEMBL8603431 0.84 CTSK (0.43) MAPK10CA1CA7CA12CA14
SCHEMBL8294662 0.84 CTSK (0.43) MAPK10CA1CA7CA12CA14
SCHEMBL22433833 0.80 MAPK10 (0.38) MAPK10CA1CA7CA12CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118005556-A COX-2 targeted inhibition photosensitizer capable of activating tumor cell apoptosis and preparation method and application thereof 大连理工大学 2024-05-10 — — CN claimed
CN-116354901-B Thiazolidinedione compound and preparation method and application thereof 郑州大学 2024-04-26 — — CN claimed
CN-116199680-B Endoperoxide compound containing GPX4 protein covalent group, and preparation method and application thereof 大连理工大学 2024-04-02 — — CN claimed
CN-116393128-B Catalyst of graphene-supported copper nanocluster and preparation process thereof 安庆长宏科技股份有限公司 2023-08-15 — — CN claimed
CN-116393128-A Catalyst of graphene-supported copper nanocluster and preparation process thereof 安庆长宏科技股份有限公司 2023-07-07 — — CN claimed
CN-116354901-A Thiazolidinedione compound and preparation method and application thereof 郑州大学 2023-06-30 — — CN claimed
CN-116199680-A Endoperoxide compound containing GPX4 protein covalent group, and preparation method and application thereof 大连理工大学 2023-06-02 — — CN claimed
CN-115637107-B Heat-resistant silicon dioxide grafted polyurethane coating and synthesis process thereof 广州豫顺新材料有限公司 2023-03-10 — — CN claimed
CN-115637107-A Heat-resistant silicon dioxide grafted polyurethane coating and synthesis process thereof 广州豫顺新材料有限公司 2023-01-24 — — CN claimed
CN-112898193-B Indole aryl sulfone derivative and preparation method and application thereof 山东大学 2022-08-05 — — CN claimed
CN-112138170-B Conjugate for preventing cisplatin drug-induced deafness and preparation method and application thereof 广东药科大学 2022-05-20 — — CN claimed
CN-110964723-B Plasmid-carrying nanoparticles for preventing and treating influenza virus and preparation method thereof 中山大学 2022-04-05 — — CN claimed
CN-111675694-B Oxime group-containing diaryl pyrimidine HIV-1 reverse transcriptase inhibitor and preparation method and application thereof 山东大学 2021-11-26 — — CN claimed
CN-106977472-B Synthesis and application of benzisoselenazolone modified nitrosourea compound 凯熙医药（天津）有限公司 2021-09-07 — — CN claimed
CN-112898193-A Indole aryl sulfone derivative and preparation method and application thereof 山东大学 2021-06-04 — — CN claimed
CN-112138170-A Conjugate for preventing cisplatin drug-induced deafness and preparation method and application thereof 广东药科大学 2020-12-29 — — CN claimed
CN-111675694-A Oxime group-containing diaryl pyrimidine HIV-1 reverse transcriptase inhibitor and preparation method and application thereof 山东大学 2020-09-18 — — CN claimed
CN-110964723-A Plasmid-carrying nanoparticles for preventing and treating influenza virus and preparation method thereof 中山大学 2020-04-07 — — CN claimed
US-20260116884-A1 PROTAC CHIMERIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF HANGZHOU ZHONGMEIHUADONG PHARMACEUTICAL CO LTD (CN) 2026-04-30 — — US disclosed
WO-1995026189-A1 AN IMPROVED METHOD OF SYNTHESIS FOR 6,9-BIS[(2-AMINOETHYL)AMINO]BENZO[g]ISOQUINOLINE-5,10-DIONE AND ITS DIMALEATE SALT BOEHRINGER MANNHEIM ITALIA, S.P.A. (US) 1995-10-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260116884-A1 PROTAC CHIMERIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF CXCR1, TXK, CXCR4 MAPK10 1708/4885CA1 2411/4885CA7 2971/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.