Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.36 |
| ▸ | MMP13 | P45452 | 3/20 | 0.36 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.36 |
| ▸ | MMP9 | P14780 | 2/20 | 0.36 |
| ▸ | COMT | P21964 | 4/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.31 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22118238 | 0.83 | ENPP3 (0.40) | MMP1MMP13ADAM17MMP9KMT2A | |
| SCHEMBL29934098 | 0.82 | PARP1 (0.40) | COMTKMT2AMEN1TDP1SMN1; SMN2 | |
| SCHEMBL19692908 | 0.82 | GRM5 (0.46) | COMTKDM4ECDK2GRM5 | |
| SCHEMBL19692927 | 0.82 | PARP1 (0.40) | COMTKMT2AMEN1TDP1SMN1; SMN2 | |
| SCHEMBL25205269 | 0.78 | ERN1 (0.35) | HTTGRM5 | |
| SCHEMBL30351121 | 0.78 | ERN1 (0.35) | HTTGRM5 | |
| SCHEMBL19692977 | 0.74 | ERN1 (0.51) | KDM4ETDP1TP53HSP90AA1SMN1; SMN2 | |
| SCHEMBL30200365 | 0.74 | ERN1 (0.51) | KDM4ETDP1TP53HSP90AA1SMN1; SMN2 | |
| SCHEMBL31716247 | 0.72 | KDM4E (0.39) | MMP1MMP13ADAM17MMP9KMT2A | |
| SCHEMBL17128052 | 0.72 | KDM4E (0.39) | MMP1MMP13ADAM17MMP9KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897842-B1 | BICYCLIC DERIVATIVES | ELANCO TIERGESUNDHEIT AG (CH) | 2025-01-29 | — | — | EP | disclosed |
| CN-113490527-B | Bicyclic derivatives | 瑞士伊兰科动物保健有限公司 | 2024-10-25 | — | — | CN | disclosed |
| US-20220064159-A1 | BICYCLIC DERIVATIVES | ELANCO TIERGESUNDHEIT AG (CH) | 2022-03-03 | — | — | US | disclosed |
| EP-3897842-A1 | BICYCLIC DERIVATIVES | Elanco Tiergesundheit AG (CH) | 2021-10-27 | — | — | EP | disclosed |
| CN-113490527-A | Bicyclic derivatives | 瑞士伊兰科动物保健有限公司 | 2021-10-08 | — | — | CN | disclosed |
| WO-2020131631-A1 | BICYCLIC DERIVATIVES | ELANCO TIERGESUNDHEIT AG (CH) | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220064159-A1 | BICYCLIC DERIVATIVES | FABP3, CYCS, PIGS | MMP1 1751/4885MMP13 2779/4885ADAM17 1461/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.