Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.31 |
| ▸ | PNP | P00491 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22118854 | 0.81 | RNASEH1 (0.34) | RNASEH1PNP | |
| SCHEMBL22119381 | 0.81 | RNASEH1 (0.34) | RNASEH1PNP | |
| SCHEMBL22118872 | 0.81 | TSHR (0.36) | RNASEH1PNP | |
| SCHEMBL22118859 | 0.80 | RNASEH1 (0.33) | RNASEH1PNP | |
| SCHEMBL22119032 | 0.79 | KDM5B (0.31) | — | |
| SCHEMBL22119310 | 0.76 | RNASEH1 (0.34) | RNASEH1PNP | |
| SCHEMBL22118821 | 0.76 | MAPT (0.34) | RNASEH1PNP | |
| Hydrochloric Acid SCHEMBL22119087 | 0.76 | PNP (0.32) | RNASEH1PNP | |
| SCHEMBL22118865 | 0.76 | PNP (0.33) | ADORA2BADORA1PNP | |
| SCHEMBL22118809 | 0.75 | RNASEH1 (0.33) | RNASEH1PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897645-A1 | DNA POLYMERASE IIIC INHIBITORS AND USE THEREOF | Acurx Pharmaceuticals, LLC (US) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020132174-A1 | DNA POLYMERASE IIIC INHIBITORS AND USE THEREOF | ACURX PHARMACEUTICALS, LLC (US) | 2020-06-25 | — | — | WO | disclosed |