Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | FOXO1 | Q12778 | 1/20 | 0.35 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22118854 | 0.87 | RNASEH1 (0.34) | PNPRNASEH1 | |
| SCHEMBL22119381 | 0.87 | RNASEH1 (0.34) | PNPRNASEH1 | |
| SCHEMBL22118974 | 0.86 | PNP (0.33) | TSHRALDH1A1MEN1KMT2APNP | |
| Hydrochloric Acid SCHEMBL22119087 | 0.86 | PNP (0.32) | PNPRNASEH1 | |
| SCHEMBL22118865 | 0.86 | PNP (0.33) | PNP | |
| SCHEMBL22118859 | 0.85 | RNASEH1 (0.33) | PNPRNASEH1 | |
| SCHEMBL22118907 | 0.85 | ALDH1A1 (0.31) | ALDH1A1PNPFOXO1RNASEH1 | |
| SCHEMBL22118816 | 0.84 | PNP (0.31) | PNP | |
| SCHEMBL22118896 | 0.83 | PNP (0.31) | PNPRNASEH1 | |
| SCHEMBL22119321 | 0.81 | PNP (0.40) | ALDH1A1PNPRNASEH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897645-A1 | DNA POLYMERASE IIIC INHIBITORS AND USE THEREOF | Acurx Pharmaceuticals, LLC (US) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020132174-A1 | DNA POLYMERASE IIIC INHIBITORS AND USE THEREOF | ACURX PHARMACEUTICALS, LLC (US) | 2020-06-25 | — | — | WO | disclosed |