Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNASEH1 | O60930 | 1/20 | 0.34 |
| ▸ | PNP | P00491 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22118854 | 0.94 | RNASEH1 (0.34) | RNASEH1PNP | |
| SCHEMBL22118859 | 0.93 | RNASEH1 (0.33) | RNASEH1PNP | |
| SCHEMBL22118809 | 0.89 | RNASEH1 (0.33) | RNASEH1PNP | |
| Hydrochloric Acid SCHEMBL22119087 | 0.88 | PNP (0.32) | RNASEH1PNP | |
| SCHEMBL22118865 | 0.88 | PNP (0.33) | PNP | |
| SCHEMBL22118872 | 0.87 | TSHR (0.36) | RNASEH1PNP | |
| SCHEMBL22118821 | 0.86 | MAPT (0.34) | RNASEH1PNP | |
| SCHEMBL22118816 | 0.86 | PNP (0.31) | PNP | |
| SCHEMBL22118878 | 0.85 | SIGMAR1 (0.39) | — | |
| SCHEMBL22119100 | 0.85 | AURKB (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897645-A1 | DNA POLYMERASE IIIC INHIBITORS AND USE THEREOF | Acurx Pharmaceuticals, LLC (US) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020132174-A1 | DNA POLYMERASE IIIC INHIBITORS AND USE THEREOF | ACURX PHARMACEUTICALS, LLC (US) | 2020-06-25 | — | — | WO | disclosed |