Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22118823 | 0.81 | KDM4E (0.42) | CYP1A2CYP2C19KDM4ERECQL | |
| SCHEMBL22118927 | 0.78 | ADORA3 (0.33) | KDM4E | |
| SCHEMBL22118787 | 0.76 | USP2 (0.30) | RECQL | |
| SCHEMBL7422513 | 0.76 | ADORA3 (0.33) | KDM4E | |
| SCHEMBL7419561 | 0.76 | ADORA3 (0.33) | KDM4E | |
| SCHEMBL22118811 | 0.70 | — | — | |
| SCHEMBL7420122 | 0.70 | CACNA1H (0.37) | CYP1A2CYP2C19KDM4E | |
| SCHEMBL22119032 | 0.69 | KDM5B (0.31) | — | |
| SCHEMBL22118872 | 0.65 | TSHR (0.36) | — | |
| SCHEMBL22119321 | 0.64 | PNP (0.40) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897645-A1 | DNA POLYMERASE IIIC INHIBITORS AND USE THEREOF | Acurx Pharmaceuticals, LLC (US) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020132174-A1 | DNA POLYMERASE IIIC INHIBITORS AND USE THEREOF | ACURX PHARMACEUTICALS, LLC (US) | 2020-06-25 | — | — | WO | disclosed |