Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | S100A9 | P06702 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22118843 | 0.90 | ALDH1A1 (0.36) | PNPPARP1ALDH1A1CSNK2A2CSNK2B | |
| SCHEMBL22118872 | 0.81 | TSHR (0.36) | PNPRNASEH1ALDH1A1 | |
| SCHEMBL22118888 | 0.80 | RNASEH1 (0.38) | RNASEH1 | |
| SCHEMBL22118946 | 0.78 | PARP1 (0.41) | PNPPARP1RNASEH1ALDH1A1S100A9 | |
| SCHEMBL22119381 | 0.78 | RNASEH1 (0.34) | PNPRNASEH1 | |
| SCHEMBL22118854 | 0.78 | RNASEH1 (0.34) | PNPRNASEH1 | |
| SCHEMBL22119310 | 0.77 | RNASEH1 (0.34) | PNPRNASEH1ALDH1A1 | |
| SCHEMBL22118895 | 0.76 | PARP1 (0.40) | PNPPARP1RNASEH1ALDH1A1L3MBTL1 | |
| SCHEMBL22118862 | 0.76 | PARP1 (0.40) | PNPPARP1RNASEH1L3MBTL1 | |
| SCHEMBL22118823 | 0.71 | KDM4E (0.42) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3897645-A1 | DNA POLYMERASE IIIC INHIBITORS AND USE THEREOF | Acurx Pharmaceuticals, LLC (US) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020132174-A1 | DNA POLYMERASE IIIC INHIBITORS AND USE THEREOF | ACURX PHARMACEUTICALS, LLC (US) | 2020-06-25 | — | — | WO | disclosed |