Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.40 |
| ▸ | GABRE | P78334 | 2/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.40 |
| ▸ | GRN | P28799 | 5/20 | 0.40 |
| ▸ | SORT1 | Q99523 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22121563 | 0.82 | MAPT (0.44) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL22150335 | 0.80 | GRN (0.37) | KDM4EGRNSORT1LMNAHTT | |
| SCHEMBL23115820 | 0.78 | SMN1; SMN2 (0.40) | KDM4ELMNAPOLB | |
| SCHEMBL23115592 | 0.78 | KDM4E (0.42) | KDM4EHTTPOLBSTING1CNR1 | |
| SCHEMBL12307407 | 0.78 | STING1 (0.44) | GRNSORT1HTTSTING1 | |
| SCHEMBL3614239 | 0.77 | KDM4E (0.51) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL23115836 | 0.77 | KDM4E (0.51) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL22121370 | 0.76 | KDM4E (0.44) | KDM4EGRNSORT1LMNAHTT | |
| SCHEMBL4754841 | 0.76 | KDM4E (0.50) | KDM4EGABRPGABRDGABRA1GABRB1 | |
| SCHEMBL22119041 | 0.75 | KDM4E (0.42) | KDM4EGABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |