Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 6/20 | 0.39 |
| ▸ | FLT1 | P17948 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23115820 | 0.82 | SMN1; SMN2 (0.40) | KDM4EALDH1A1MAPTPOLB | |
| SCHEMBL22121357 | 0.78 | KDM4E (0.49) | KDM4EF10STING1HTTCNR1 | |
| SCHEMBL23115764 | 0.75 | KDM4E (0.48) | KDM4EALDH1A1PKMF10STING1 | |
| SCHEMBL23115923 | 0.74 | ALDH1A1 (0.53) | KDM4EALDH1A1PKMSTING1MAPT | |
| SCHEMBL23115954 | 0.73 | KDM4E (0.33) | KDM4EALDH1A1PKMHTTPOLB | |
| SCHEMBL22121370 | 0.72 | KDM4E (0.44) | KDM4EALDH1A1PKMHTTPOLB | |
| SCHEMBL23116107 | 0.72 | GPR119 (0.36) | KDM4EALDH1A1HTTPOLB | |
| SCHEMBL3519480 | 0.71 | KDM4E (0.47) | KDM4EALDH1A1PKMSMYD3POLB | |
| SCHEMBL22121563 | 0.69 | MAPT (0.44) | KDM4EALDH1A1STING1MAPTPOLB | |
| SCHEMBL12307407 | 0.69 | STING1 (0.44) | ALDH1A1STING1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12297190-B2 | Modulators of STING (stimulator of interferon genes) | PFIZER INC. (US) | 2025-05-13 | — | — | US | disclosed |
| EP-4034534-A1 | POLYHETEROCYCLIC MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | Pfizer Inc. (US) | 2022-08-03 | — | — | EP | disclosed |
| CN-114728946-A | Polyheterocyclic modulators of STING (stimulator of interferon genes) | 辉瑞公司 | 2022-07-08 | — | — | CN | disclosed |
| WO-2021059136-A1 | POLYHETEROCYCLIC MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2021-04-01 | — | — | WO | disclosed |
| WO-2021059136-A1 | POLYHETEROCYCLIC MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2021-04-01 | — | — | WO | disclosed |
| US-20210087180-A1 | Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2021-03-25 | — | — | US | disclosed |
| US-20210087180-A1 | Modulators of STING (Stimulator of Interferon Genes) | PFIZER INC. (US) | 2021-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12297190-B2 | Modulators of STING (stimulator of interferon genes) | STING1, IRF3, CGAS | KDM4E 3785/4885ALDH1A1 4800/4885PKM 2940/4885 |
| US-20210087180-A1 | Modulators of STING (Stimulator of Interferon Genes) | STING1, IRF3, CGAS | KDM4E 3785/4885ALDH1A1 4800/4885PKM 2940/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.