Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRN | P28799 | 5/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | APAF1 | O14727 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.31 |
| ▸ | FLT1 | P17948 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22150499 | 0.83 | TDP1 (0.41) | GRNSORT1ALDH1A1MEN1GAA | |
| SCHEMBL22121357 | 0.80 | KDM4E (0.49) | GRNSORT1KDM4ELMNAAPAF1 | |
| SCHEMBL22151650 | 0.76 | KDM4E (0.41) | ALDH1A1MEN1GAAKMT2AKDM4E | |
| SCHEMBL2518853 | 0.75 | HCAR3 (0.45) | GRNSORT1ALDH1A1MEN1GAA | |
| SCHEMBL22151409 | 0.75 | KDM4E (0.40) | ALDH1A1MEN1GAAKMT2AKDM4E | |
| SCHEMBL12307407 | 0.74 | STING1 (0.44) | GRNSORT1ALDH1A1MEN1GAA | |
| SCHEMBL21628345 | 0.74 | GRN (0.40) | GRNSORT1ALDH1A1MEN1GAA | |
| SCHEMBL798561 | 0.74 | GRN (0.49) | GRNSORT1ALDH1A1MEN1GAA | |
| SCHEMBL22932727 | 0.73 | CNR1 (0.42) | ALDH1A1MEN1GAAKMT2AKDM4E | |
| SCHEMBL31068479 | 0.72 | ALDH1A1 (0.43) | GRNSORT1ALDH1A1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132582-A1 | STING AGONISTS AND USES THEREOF | NIMBUS TITAN, INC. (US) | 2020-06-25 | — | — | WO | disclosed |