Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28615279 | 0.76 | HSP90AB1 (0.41) | DGAT1HTR1AHTR7PARP1ALDH1A1 | |
| SCHEMBL28466149 | 0.73 | HPGD (0.40) | DGAT1HTR1AHTR7PARP1ALDH1A1 | |
| SCHEMBL3026191 | 0.73 | DGAT1 (0.47) | DGAT1HTR1AHTR7PARP1ALDH1A1 | |
| SCHEMBL28624518 | 0.71 | HTR7 (0.46) | HTR1AHTR7ALDH1A1KMT2A | |
| SCHEMBL811064 | 0.68 | DGAT1 (0.52) | DGAT1PARP1ALDH1A1KMT2A | |
| SCHEMBL24630649 | 0.66 | DGAT1 (0.48) | DGAT1ALDH1A1KMT2A | |
| SCHEMBL30124998 | 0.66 | DGAT1 (0.48) | DGAT1ALDH1A1KMT2A | |
| SCHEMBL671054 | 0.66 | KMT2A (0.48) | DGAT1ALDH1A1KMT2A | |
| SCHEMBL21357388 | 0.66 | KMT2A (0.51) | DGAT1ALDH1A1KMT2A | |
| SCHEMBL21357386 | 0.66 | KMT2A (0.51) | DGAT1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898633-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2021-10-27 | — | — | EP | disclosed |
| WO-2020127504-A1 | SUBSTITUTED OXOPYRIDINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-25 | — | — | WO | disclosed |