Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28624518 | 0.90 | HTR7 (0.46) | HPGDALDH1A1HSD17B3HTR7HTR1A | |
| SCHEMBL28615279 | 0.86 | HSP90AB1 (0.41) | ALDH1A1HTR7HTR1ADGAT1LMNA | |
| SCHEMBL28477388 | 0.80 | PARP1 (0.36) | HPGDALDH1A1TSHRRECQLLMNA | |
| SCHEMBL22123487 | 0.79 | ALDH1A1 (0.42) | HPGDALDH1A1ALOX15TSHRRECQL | |
| SCHEMBL3026191 | 0.76 | DGAT1 (0.47) | HPGDALDH1A1TSHRHSD17B10HTR7 | |
| SCHEMBL10975649 | 0.74 | ALDH1A1 (0.47) | HPGDALDH1A1ALOX15TSHRRECQL | |
| SCHEMBL28024920 | 0.73 | PARP1 (0.38) | HPGDALDH1A1ALOX15TSHRRECQL | |
| SCHEMBL22123647 | 0.73 | DGAT1 (0.36) | ALDH1A1HTR7HTR1ADGAT1PARP1 | |
| SCHEMBL7761149 | 0.73 | LMNA (0.49) | HPGDALDH1A1ALOX15TSHRRECQL | |
| SCHEMBL811064 | 0.71 | DGAT1 (0.52) | HPGDALDH1A1TSHRRECQLHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292539-B | Substituted oxopyridine derivatives | 拜耳制药股份公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-113292539-A | Substituted oxopyridine derivatives | 拜耳制药股份公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-108026072-B | Substituted oxopyridine derivatives | 拜耳制药股份公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-111770917-A | Two 4- { [ (2S) -2- {4- [ 5-chloro-2- (1H-1,2, 3-triazol-1-yl) phenyl ] -5-methoxy-2-oxopyridin-1 (2H) -yl } butyryl ] amino } -2-fluorobenzamide derivatives | 拜耳股份公司 | 2020-10-13 | — | — | CN | disclosed |