Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.45 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | UGT2B7 | P16662 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 4/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20207777 | 1.00 | NOS3 (0.45) | NOS3NOS1UGT2B7ALDH1A1PTPN5 | |
| Acetic Acid SCHEMBL9711169 | 0.89 | NOS3 (0.42) | NOS3NOS1UGT2B7ALDH1A1PTPN5 | |
| SCHEMBL9331190 | 0.85 | NOS3 (0.54) | NOS3NOS1UGT2B7ALDH1A1PTPN5 | |
| SCHEMBL9331061 | 0.85 | NOS3 (0.54) | NOS3NOS1UGT2B7ALDH1A1PTPN5 | |
| SCHEMBL40655 | 0.85 | NOS3 (0.54) | NOS3NOS1UGT2B7ALDH1A1PTPN5 | |
| SCHEMBL9331652 | 0.85 | NOS3 (0.54) | NOS3NOS1UGT2B7ALDH1A1PTPN5 | |
| SCHEMBL2643393 | 0.78 | NOS3 (0.45) | NOS3NOS1UGT2B7ALDH1A1PTPN5 | |
| SCHEMBL9293367 | 0.77 | ESR1 (0.52) | ESR1PDCD1ESR2CD274IDO1 | |
| SCHEMBL590373 | 0.77 | TYR (0.46) | ALDH1A1IDO1KDM4ELMNAHIF1A | |
| SCHEMBL114216 | 0.77 | UGT2B7 (0.52) | NOS3NOS1UGT2B7ALDH1A1PTPN5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0271307-B1 | METHOD FOR PRODUCING ALKENYLTHIOPHENOLS AND THEIR ESTERS | HOECHST CELANESE CORPORATION (US) | 1992-01-02 | — | — | EP | claimed |
| US-4794205-A | Method for producing alkenylthiophenols and their esters | HOECHST CELANESE CORPORATION (US) | 1988-12-27 | — | — | US | claimed |
| WO-2023125907-A1 | DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INHIBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE | BEIGENE, LTD. (KY) | 2023-07-06 | — | — | WO | disclosed |
| CN-111517902-A | Aerobic oxidation system containing sulfinic acid, sulfonic acid or derivatives thereof and photo-oxidation promoting method thereof | 清华大学 | 2020-08-11 | — | — | CN | disclosed |
| US-20180185382-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | CASE WESTERN RESERVE UNIVERSITY | 2018-07-05 | — | — | US | disclosed |
| US-9329185-B2 | Sulfonate compounds | UNIVERSITY OF MASSACHUSETTS (US) | 2016-05-03 | — | — | US | disclosed |
| US-20140275526-A1 | SULFONATE COMPOUNDS | UNIVERSITY OF MASSACHUSETTS (US) | 2014-09-18 | — | — | US | disclosed |
| US-8765789-B2 | 2-pyridinecarboxamide derivatives | MSD K.K. (JP) | 2014-07-01 | — | — | US | disclosed |
| US-20130085156-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | MSD K.K. (JP) | 2013-04-04 | — | — | US | disclosed |
| US-8344003-B2 | 2-pyridinecarboxamide derivatives | MSD K. K. (JP) | 2013-01-01 | — | — | US | disclosed |
| EP-1598349-B1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | MSD KK (JP) | 2011-07-27 | — | — | EP | disclosed |
| US-20060258701-A1 | Novel 2-pyridinecarboxamide derivatives | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-11-16 | — | — | US | disclosed |
| US-20060167053-A1 | Heteroarylcarbamoylbenzene derivative | MSD K.K. (JP) | 2006-07-27 | — | — | US | disclosed |
| CN-1747951-A | Novel 2-pyridinecarboxamide derivatives | BANYU PHARMA CO LTD (JP) | 2006-03-15 | — | — | CN | disclosed |
| EP-1600442-A1 | HETEROARYLCARBAMOYLBENZENE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-30 | — | — | EP | disclosed |
| EP-1598349-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2005-11-23 | — | — | EP | disclosed |
| EP-0271307-B1 | METHOD FOR PRODUCING ALKENYLTHIOPHENOLS AND THEIR ESTERS | HOECHST CELANESE CORPORATION (US) | 1992-01-02 | — | — | EP | disclosed |
| US-4794205-A | Method for producing alkenylthiophenols and their esters | HOECHST CELANESE CORPORATION (US) | 1988-12-27 | — | — | US | disclosed |
| US-4794205-A | Method for producing alkenylthiophenols and their esters | HOECHST CELANESE CORPORATION (US) | 1988-12-27 | — | — | US | disclosed |
| EP-0271307-A2 | Method for producing alkenylthiophenols and their esters | HOECHST CELANESE CORPORATION (US) | 1988-06-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180185382-A1 | COMPOSITIONS AND METHODS FOR TREATING CANCER | PPP2CA, PPP3CA, PPP4C | NOS3 3130/4885NOS1 3390/4885UGT2B7 4384/4885 |
| US-20130085156-A1 | NOVEL 2-PYRIDINECARBOXAMIDE DERIVATIVES | GCKR, GCK, HK2 | NOS3 1046/4885NOS1 1423/4885UGT2B7 667/4885 |
| US-20060167053-A1 | Heteroarylcarbamoylbenzene derivative | GCK, GCKR, GALK1 | NOS3 2621/4885NOS1 3130/4885UGT2B7 42/4885 |
| US-20060258701-A1 | Novel 2-pyridinecarboxamide derivatives | GCKR, GCK, HK2 | NOS3 1081/4885NOS1 1500/4885UGT2B7 675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.