Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA9 | Q16790 | 4/20 | 0.46 |
| ▸ | PREP | P48147 | 4/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1828057 | 0.80 | CA12 (0.47) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL3690504 | 0.80 | CA12 (0.47) | CA12CA1CA9PREP | |
| SCHEMBL17836741 | 0.79 | CA12 (0.46) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL28422272 | 0.79 | CA12 (0.46) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL2090369 | 0.78 | CA12 (0.49) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL2023774 | 0.77 | CA12 (0.45) | CA12CA1CA9PREP | |
| SCHEMBL9013589 | 0.76 | CA12 (0.47) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL6765739 | 0.76 | CA12 (0.47) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL6841139 | 0.76 | CA12 (0.48) | CA12CA1CA9PREPHSP90AA1 | |
| SCHEMBL2292629 | 0.76 | CA12 (0.44) | CA12CA1CA9PREPHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11407725-B2 | Selective fluorescent probe for aldehyde dehydrogenase | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2022-08-09 | — | — | US | disclosed |
| US-20200199092-A1 | SELECTIVE FLUORESCENT PROBE FOR ALDEHYDE DEHYDROGENASE | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2020-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11407725-B2 | Selective fluorescent probe for aldehyde dehydrogenase | ALDH1A1, ALDH3A1, ALDH16A1 | CA12 1774/4885CA1 1061/4885CA9 1735/4885 |
| US-20200199092-A1 | SELECTIVE FLUORESCENT PROBE FOR ALDEHYDE DEHYDROGENASE | ALDH1A1, ALDH3A1, ALDH16A1 | CA12 1774/4885CA1 1061/4885CA9 1735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.