Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 1/20 | 0.52 | |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.48 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.47 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22128494 | 1.00 | PDF (0.52) | PDFALDH1A1SMN1; SMN2GLASIRT5 | |
| SCHEMBL30458236 | 0.93 | ALDH1A1 (0.58) | PDFALDH1A1SMN1; SMN2GLASIRT5 | |
| SCHEMBL20303925 | 0.86 | CA1 (0.61) | PDFALDH1A1SMN1; SMN2GLASIRT5 | |
| SCHEMBL20303929 | 0.86 | CA1 (0.61) | PDFALDH1A1SMN1; SMN2GLASIRT5 | |
| SCHEMBL20303609 | 0.85 | PDF (0.69) | PDFALDH1A1SMN1; SMN2GLASIRT1 | |
| SCHEMBL20303610 | 0.85 | PDF (0.69) | PDFALDH1A1SMN1; SMN2GLASIRT1 | |
| SCHEMBL29378049 | 0.85 | PDF (0.51) | PDFALDH1A1SMN1; SMN2GLASIRT5 | |
| Hydrochloric Acid SCHEMBL31456028 | 0.84 | PDF (0.68) | PDFALDH1A1SMN1; SMN2GLASIRT1 | |
| SCHEMBL22148637 | 0.81 | SSTR3 (0.55) | PDFALDH1A1SIRT1SSTR3 | |
| SCHEMBL29400619 | 0.81 | CA1 (0.51) | PDFALDH1A1SMN1; SMN2GLASIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11879019-B2 | Dual-enzyme responsive peptides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2024-01-23 | — | — | US | disclosed |
| US-20200199177-A1 | Dual-Enzyme Responsive Peptides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2020-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11879019-B2 | Dual-enzyme responsive peptides | DNPEP, PEPD, APEH | PDF 321/4885ALDH1A1 680/4885SMN1; SMN2 4488/4885 |
| US-20200199177-A1 | Dual-Enzyme Responsive Peptides | DNPEP, PEPD, APEH | PDF 321/4885ALDH1A1 680/4885SMN1; SMN2 4488/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.