Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.61 |
| ▸ | CA2 | P00918 | 5/20 | 0.61 |
| ▸ | Q9HBH1 | 1/20 | 0.50 | |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20303925 | 1.00 | CA1 (0.61) | CA1CA2PDFSIRT5GLA | |
| SCHEMBL29400619 | 0.92 | CA1 (0.51) | CA1CA2PDFSIRT5GLA | |
| SCHEMBL30458236 | 0.88 | ALDH1A1 (0.58) | CA1CA2PDFSIRT5GLA | |
| SCHEMBL22128494 | 0.86 | PDF (0.52) | CA1CA2PDFSIRT5GLA | |
| SCHEMBL22128495 | 0.86 | PDF (0.52) | CA1CA2PDFSIRT5GLA | |
| SCHEMBL30746081 | 0.85 | DPP8 (0.48) | CA1CA2PDFGLAALDH1A1 | |
| SCHEMBL20067639 | 0.85 | CA1 (0.64) | CA1CA2SIRT5GLASIRT1 | |
| SCHEMBL29400857 | 0.84 | SIRT5 (0.56) | SIRT5SIRT1MAPT | |
| SCHEMBL8377514 | 0.83 | PDF (0.65) | CA1CA2PDFSIRT5ALDH1A1 | |
| SCHEMBL8379032 | 0.83 | PDF (0.49) | CA1CA2PDFSIRT5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3555280-A1 | DUAL-ENZYME RESPONSIVE PEPTIDES | The Regents of The University of California (US) | 2019-10-23 | — | — | EP | disclosed |
| WO-2018118902-A1 | DUAL-ENZYME RESPONSIVE PEPTIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-06-28 | — | — | WO | disclosed |