Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 8/20 | 0.35 |
| ▸ | FNTB | P49356 | 8/20 | 0.35 |
| ▸ | OXTR | P30559 | 3/20 | 0.34 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.34 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.34 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.34 |
| ▸ | PGGT1B | P53609 | 5/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3377153 | 0.81 | LMNA (0.56) | MEN1KMT2ALMNAALDH1A1OXTR | |
| SCHEMBL2212915 | 0.80 | MEN1 (0.58) | MEN1KMT2ALMNAALDH1A1FNTA | |
| SCHEMBL3379804 | 0.80 | LMNA (0.57) | MEN1KMT2ALMNAALDH1A1OXTR | |
| SCHEMBL3377068 | 0.79 | LMNA (0.58) | MEN1KMT2ALMNAALDH1A1GRM2 | |
| SCHEMBL2212615 | 0.77 | FNTA (0.51) | MEN1KMT2ALMNAALDH1A1FNTA | |
| SCHEMBL2211492 | 0.73 | MEN1 (0.53) | MEN1KMT2ALMNAALDH1A1FNTA | |
| SCHEMBL2214180 | 0.72 | MEN1 (0.54) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL2211059 | 0.71 | CXCR3 (0.40) | MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL304042 | 0.70 | MAPT (0.46) | MEN1KMT2ALMNAALDH1A1OXTR | |
| SCHEMBL3378155 | 0.70 | FNTA (0.44) | MEN1KMT2ALMNAALDH1A1FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342177-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | Xention Limited (GB) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010023448-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | XENTION LIMITED (GB) | 2010-03-04 | — | — | WO | disclosed |