Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30937500 | 1.00 | GAA (0.36) | GAAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL29006384 | 0.89 | GAA (0.40) | GAAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL28024269 | 0.89 | GAA (0.40) | GAAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL30821590 | 0.87 | IDO1 (0.39) | GAANPC1RAB9AIDO1TDO2 | |
| SCHEMBL29006385 | 0.86 | FFAR4 (0.36) | GAAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL22129184 | 0.82 | DPP4 (0.37) | — | |
| SCHEMBL30075904 | 0.82 | DPP4 (0.37) | — | |
| SCHEMBL31005301 | 0.82 | CYP19A1 (0.36) | GAAIDO1TDO2CYP19A1CYP11B1 | |
| SCHEMBL30771980 | 0.79 | ALDH1A1 (0.39) | GAAMEN1KMT2AIDO1TDO2 | |
| SCHEMBL14878840 | 0.78 | CYP3A4 (0.35) | ALDH1A1TP53CYP3A4TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118146271-A | Fluoro diphenyl methyl acenaphthene diimine nickel complex and its preparation method and use | 中国科学院化学研究所 | 2024-06-07 | — | — | CN | disclosed |
| WO-2020124557-A1 | VINYLIDENE ACENAPHTHENE α-DIIMINE NICKEL OLEFIN CATALYST AND PREPARATION METHOD AND APPLICATION THEREOF | 杭州星庐科技有限公司 | 2020-06-25 | — | — | WO | disclosed |
| WO-2020124556-A1 | ASYMMETRIC (ALPHA-DIIMINE)NICKEL OLEFIN CATALYST, AND PREPARATION METHOD AND APPLICATION THEREOF | 杭州星庐科技有限公司 | 2020-06-25 | — | — | WO | disclosed |