SCHEMBL29006384

SCHEMBL29006384

Cc1cc(C(c2ccc(F)cc2)c2ccc(F)cc2)cc(C)c1N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.40
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
TSHR P16473 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
IDO1 P14902 2/20 0.38
TDO2 P48775 2/20 0.38
ACHE P22303 1/20 0.36
CYP19A1 P11511 2/20 0.35
CYP11B1 P15538 2/20 0.35
CYP11B2 P19099 2/20 0.35
POLB P06746 1/20 0.34
AOC3 Q16853 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
PTGDR2 Q9Y5Y4 1/20 0.33
GRM5 P41594 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28024269 1.00 GAA (0.40) GAAALDH1A1TP53CYP3A4TSHR
SCHEMBL22129252 0.89 GAA (0.36) GAAALDH1A1TP53CYP3A4TSHR
SCHEMBL30937500 0.89 GAA (0.36) GAAALDH1A1TP53CYP3A4TSHR
SCHEMBL30771980 0.85 ALDH1A1 (0.39) GAAALDH1A1IDO1TDO2CYP19A1
SCHEMBL22050675 0.83 ALDH1A1 (0.48) GAAALDH1A1TP53CYP3A4TSHR
SCHEMBL13523900 0.83 ALDH1A1 (0.43) GAAALDH1A1TP53CYP3A4TSHR
SCHEMBL3688289 0.82 LMNA (0.42) GAAALDH1A1TP53CYP3A4TSHR
SCHEMBL15134980 0.80 PTGS1 (0.52) GAAACHEPOLBKMT2APTGS1
SCHEMBL22550574 0.80 ESR1 (0.41) GAAALDH1A1TP53CYP3A4TSHR
SCHEMBL28205472 0.79 ALDH1A1 (0.42) GAAALDH1A1TP53CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080084-A Preparation of alpha-diimine nickel complex and application of alpha-diimine nickel complex in olefin polymerization 2026-05-26 CN disclosed
CN-116178207-B Preparation method and application of symmetrical camphoryl alpha-diimine nickel complex with high thermal stability 中国科学院化学研究所 2025-05-16 CN disclosed
CN-117510554-A Alpha-diimine nickel complex catalyst, preparation method and application thereof 北京服装学院 2024-02-06 CN disclosed
CN-116178207-A Preparation method and application of symmetrical camphoryl alpha-diimine nickel complex with high thermal stability 中国科学院化学研究所 2023-05-30 CN disclosed
CN-115819469-A High-activity transition metal iron complex, preparation method and application thereof 中国科学院化学研究所 2023-03-21 CN disclosed
CN-115385966-A High-activity transition metal cobalt complex, preparation method and application thereof 中国科学院化学研究所 2022-11-25 CN disclosed