SCHEMBL29006385

SCHEMBL29006385

Cc1cc(C)c(N)c(C(c2ccc(F)cc2)c2ccc(F)cc2)c1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.36
GAA P10253 1/20 0.36
ACHE P22303 1/20 0.35
RAPGEF4 Q8WZA2 2/20 0.33
IDO1 P14902 2/20 0.33
TDO2 P48775 2/20 0.33
KDM4E B2RXH2 1/20 0.33
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
PTGDR2 Q9Y5Y4 1/20 0.31
MEN1 O00255 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
AOC3 Q16853 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22129252 0.86 GAA (0.36) GAAACHEIDO1TDO2PTGDR2
SCHEMBL30937500 0.86 GAA (0.36) GAAACHEIDO1TDO2PTGDR2
SCHEMBL31619726 0.85 MEN1 (0.38) GAAACHEIDO1TDO2MEN1
SCHEMBL30838420 0.83 RAPGEF4 (0.38) GAAACHERAPGEF4KDM4EPTGS1
SCHEMBL31403354 0.83 RAPGEF4 (0.40) RAPGEF4KDM4EMEN1NPC1KMT2A
SCHEMBL29283591 0.83 ADRB2 (0.38) FFAR4RAPGEF4IDO1TDO2KDM4E
SCHEMBL30506418 0.82 SLC6A2 (0.41) FFAR4GAAKDM4E
SCHEMBL22050676 0.82 ALDH1A1 (0.37) GAAKDM4EMEN1KMT2A
SCHEMBL27840493 0.82 SLC6A2 (0.41) FFAR4GAAKDM4E
SCHEMBL31403366 0.82 RAPGEF4 (0.35) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178207-B Preparation method and application of symmetrical camphoryl alpha-diimine nickel complex with high thermal stability 中国科学院化学研究所 2025-05-16 CN disclosed
CN-119552177-A Asymmetric diimine zinc complex and preparation method and application thereof 浙江巨化技术中心有限公司 2025-03-04 CN disclosed
CN-117510375-A Diimine ligand, preparation method and application thereof 浙江巨化技术中心有限公司 2024-02-06 CN disclosed
CN-116239494-A Ligand compound and preparation method thereof, catalyst composition and application, catalyst and polyethylene elastomer and preparation method and application thereof 浙江巨化技术中心有限公司 2023-06-09 CN disclosed
CN-116178207-A Preparation method and application of symmetrical camphoryl alpha-diimine nickel complex with high thermal stability 中国科学院化学研究所 2023-05-30 CN disclosed
CN-115819469-A High-activity transition metal iron complex, preparation method and application thereof 中国科学院化学研究所 2023-03-21 CN disclosed
CN-115385966-A High-activity transition metal cobalt complex, preparation method and application thereof 中国科学院化学研究所 2022-11-25 CN disclosed