Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22864673 | 0.80 | BRD4 (0.37) | BRD4 | |
| SCHEMBL31378040 | 0.80 | BRD4 (0.37) | BRD4 | |
| SCHEMBL22130447 | 0.75 | NOTUM (0.49) | — | |
| SCHEMBL22130448 | 0.74 | NPY5R (0.41) | — | |
| SCHEMBL6448185 | 0.72 | BRD4 (0.39) | BRD4 | |
| SCHEMBL29897781 | 0.72 | BRD4 (0.39) | BRD4 | |
| SCHEMBL29897761 | 0.71 | KDM4E (0.43) | BRD4 | |
| SCHEMBL20506587 | 0.71 | KDM4E (0.43) | BRD4 | |
| SCHEMBL22864629 | 0.70 | BRD4 (0.38) | BRD4 | |
| SCHEMBL9364772 | 0.65 | BRD4 (0.59) | BRD4KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10688080-B2 | Compositions, methods of use, and methods of treatment | UNIVERSITY OF SOUTH FLORIDA (US) | 2020-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10688080-B2 | Compositions, methods of use, and methods of treatment | LIPA, LCT, GAA | NR3C1 4636/4885BRD4 3752/4885KCNH2 3196/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.