Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24450924 | 0.93 | TRPM2 (0.51) | TRPM2 | |
| SCHEMBL22133756 | 0.88 | TRPM2 (0.66) | TRPM2 | |
| SCHEMBL22133475 | 0.81 | CYP1A2 (0.50) | TRPM2 | |
| SCHEMBL22133480 | 0.80 | TRPM2 (0.62) | TRPM2 | |
| SCHEMBL24450908 | 0.80 | TRPM2 (0.62) | TRPM2 | |
| SCHEMBL22133488 | 0.77 | TRPM2 (0.64) | TRPM2 | |
| SCHEMBL2292939 | 0.76 | — | — | |
| SCHEMBL24450937 | 0.75 | TRPM2 (0.80) | TRPM2 | |
| SCHEMBL20711287 | 0.75 | IMPDH2 (0.52) | — | |
| SCHEMBL22133474 | 0.75 | TRPM2 (0.80) | TRPM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132603-A2 | SALICYL-ADENOSINEMONOSULFAMATE ANALOGS AND USES THEREOF | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2020-06-25 | — | — | WO | disclosed |