Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.30 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32675754 | 1.00 | NPC1 (0.33) | NPC1RAB9AKMT2AHSD17B10TGFBR1 | |
| SCHEMBL24141636 | 0.76 | USP1 (0.32) | — | |
| SCHEMBL24141600 | 0.76 | FEN1 (0.33) | NPC1RAB9A | |
| SCHEMBL26520751 | 0.70 | CCR1 (0.56) | TGFBR1 | |
| SCHEMBL150058 | 0.70 | — | — | |
| SCHEMBL502824 | 0.68 | — | — | |
| SCHEMBL28663560 | 0.67 | KDM4E (0.57) | NPC1RAB9AKMT2AHSD17B10 | |
| SCHEMBL16189662 | 0.66 | — | — | |
| SCHEMBL18396875 | 0.66 | ALDH1A1 (0.55) | NPC1RAB9AKMT2AHSD17B10 | |
| SCHEMBL9355994 | 0.66 | CCR1 (0.67) | NPC1RAB9AHSD17B10TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132504-A1 | 3.ALPHA.-HYDROXY-17.BETA.-AMIDE NEUROACTIVE STEROIDS AND COMPOSITIONS THEREOF | SAGE THERAPEUTICS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |