SCHEMBL22136235

SCHEMBL22136235

CC1C=CC(N(c2ccccc2)c2ccc(-c3ccc(N(c4ccccc4)c4ccccc4)cc3)cc2)=CC1

nearest known ligand 0.35

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MEN1 O00255 1/20 0.31
CRHBP P24387 1/20 0.31
KMT2A Q03164 1/20 0.31
ATM Q13315 1/20 0.31
CRHR2 Q13324 1/20 0.31
TLR9 Q9NR96 1/20 0.31
APP P05067 2/20 0.31
TNK2 Q07912 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29345361 0.97 GPR88 (0.32) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL18523979 0.95 ALDH1A1 (0.38) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL13968324 0.92 ALDH1A1 (0.32) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL19593121 0.92 ALDH1A1 (0.32) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL22298359 0.92 RELA (0.37) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL25642559 0.91
SCHEMBL25056942 0.89
SCHEMBL22781125 0.89 HPGD (0.33)
SCHEMBL19942830 0.89
SCHEMBL12807410 0.89 APP (0.35) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3741763-B1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2021-08-18 EP disclosed
EP-3671884-A1 ORGANIC LIGHT-EMITTING DEVICE AND DISPLAY APPARATUS COMPRISING THE SAME Samsung Display Co., Ltd. (KR) 2020-06-24 EP disclosed