SCHEMBL2213636

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2212610	0.89	TDO2 (0.36)	ABCG2KITCYP1B1MAPT
	SCHEMBL2216620	0.85	TDO2 (0.42)	PDGFRBPDGFRAABCG2DHPSCYP1A1
	SCHEMBL2836126	0.84	TDO2 (0.46)	ABCG2KDM4EALDH1A1MAPT
	SCHEMBL12330282	0.81	TRPM8 (0.42)	TRPM8KDM4E
	SCHEMBL2242688	0.79	IDO1 (0.42)	ABCG2CYP1A1CYP1A2CYP1B1FYN
	SCHEMBL2215084	0.79	NPC1 (0.52)	ABCG2CYP1A2KDM4EALDH1A1MAPT
	SCHEMBL2216607	0.78	NPC1 (0.40)	PDGFRBPDGFRAABCG2CYP1A2KDM4E
	SCHEMBL12958858	0.77	ESR2 (0.47)	ABCG2TRPM8KDM4EMAPTTP53
	SCHEMBL2843197	0.76	CCR1 (0.39)	CYP1A1CYP1A2CYP1B1KDM4EALDH1A1
	SCHEMBL1812558	0.76	PDGFRB (0.48)	PDGFRBPDGFRAABCG2DHPSRELA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.