SCHEMBL2216620

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2242688	0.89	IDO1 (0.42)	TDO2IDO1MAPTTP53CYP1A1
	SCHEMBL2212610	0.88	TDO2 (0.36)	TDO2IDO1MAPTCYP1B1ABCG2
	SCHEMBL13385250	0.86	DHPS (0.40)	TDO2DHPSPDGFRBPDGFRAIDO1
	SCHEMBL2836126	0.86	TDO2 (0.46)	TDO2IDO1MAPTABCG2SMN1; SMN2
	SCHEMBL2216607	0.85	NPC1 (0.40)	PDGFRBPDGFRAMAPTABCG2SMN1; SMN2
	SCHEMBL8145959	0.85	DHPS (0.40)	TDO2DHPSPDGFRBPDGFRAIDO1
	SCHEMBL2213636	0.85	PDGFRB (0.44)	DHPSPDGFRBPDGFRAMAPTTP53
	SCHEMBL13502213	0.82	MAPT (0.40)	TDO2DHPSPDGFRBPDGFRAIDO1
	SCHEMBL13385241	0.82	MAPT (0.38)	TDO2DHPSPDGFRBPDGFRAIDO1
	SCHEMBL2215084	0.78	NPC1 (0.52)	MAPTTP53ABCG2SMN1; SMN2ABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.