SCHEMBL22137152

SCHEMBL22137152

Nc1cccc2c3c(-c4ccccc4)cccc3n(-c3ccccc3)c12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.42
HSD17B10 Q99714 1/20 0.42
KMT2A Q03164 5/20 0.41
KDM4E B2RXH2 3/20 0.41
MAPT P10636 3/20 0.41
KEAP1 Q14145 3/20 0.41
NFE2L2 Q16236 3/20 0.41
HTT P42858 2/20 0.41
USP2 O75604 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
L3MBTL1 Q9Y468 3/20 0.41
ATM Q13315 1/20 0.41
IL1R1 P14778 1/20 0.38
MEN1 O00255 3/20 0.38
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
MAP4K4 O95819 1/20 0.36
CSF1R P07333 1/20 0.36
FGFR1 P11362 1/20 0.36
PDGFRA P16234 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22137187 0.88 ALDH1A1 (0.42) ALDH1A1HSD17B10KMT2AKDM4EMAPT
SCHEMBL23627791 0.86 KDM4E (0.47) ALDH1A1HSD17B10KMT2AKDM4EMAPT
SCHEMBL26191626 0.82 MAPK14 (0.45) ALDH1A1KMT2AKDM4EMAPTHTT
SCHEMBL19011033 0.82 ALKBH5 (0.41) ALDH1A1HSD17B10KMT2AKDM4EMAPT
SCHEMBL22137016 0.81 ALDH1A1 (0.47) ALDH1A1HSD17B10KMT2AKDM4EMAPT
SCHEMBL21042125 0.81 ALDH1A1 (0.47) ALDH1A1HSD17B10KMT2AKDM4EMAPT
SCHEMBL23659682 0.81 L3MBTL1 (0.40) ALDH1A1HSD17B10KMT2AKDM4EMAPT
SCHEMBL16491725 0.81 L3MBTL1 (0.59) ALDH1A1HSD17B10KMT2AKDM4EMAPT
SCHEMBL22426340 0.80 L3MBTL1 (0.39) ALDH1A1HSD17B10KMT2AKDM4EMAPT
SCHEMBL23008071 0.80 L3MBTL1 (0.46) ALDH1A1KMT2AKDM4EMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3670520-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2022-01-12 EP disclosed
EP-3712145-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING SUCH COMPOUND Samsung Electronics Co., Ltd. (KR) 2020-09-23 EP disclosed
EP-3670520-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND Samsung Electronics Co., Ltd. (KR) 2020-06-24 EP disclosed