Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | XBP1 | P17861 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8204552 | 0.84 | BRD4 (0.62) | ALDH1A1MAPK1HPGDXBP1CYP1A2 | |
| SCHEMBL22137275 | 0.84 | ALDH1A1 (0.54) | ALDH1A1MAPK1HPGDXBP1CYP1A2 | |
| SCHEMBL1450411 | 0.78 | HPGD (0.80) | ALDH1A1MAPK1HPGDXBP1CYP1A2 | |
| SCHEMBL22137301 | 0.77 | RAB9A (0.59) | ALDH1A1MAPK1CYP2C9L3MBTL1MAPT | |
| SCHEMBL1126546 | 0.75 | HPGD (0.64) | ALDH1A1MAPK1HPGDXBP1CYP1A2 | |
| SCHEMBL2150867 | 0.74 | CYP1A2 (0.68) | ALDH1A1MAPK1HPGDXBP1CYP1A2 | |
| SCHEMBL13925261 | 0.72 | CYP1A2 (0.44) | ALDH1A1MAPK1HPGDCYP1A2CYP2C9 | |
| SCHEMBL26088749 | 0.71 | HPGD (0.56) | ALDH1A1MAPK1HPGDXBP1CYP1A2 | |
| SCHEMBL5203823 | 0.71 | ALDH1A1 (1.00) | ALDH1A1MAPK1HPGDXBP1CYP1A2 | |
| SCHEMBL69310 | 0.71 | HPGD (1.00) | ALDH1A1MAPK1HPGDXBP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3898587-B1 | CONDENSED PYRROLES AS NOVEL BROMODOMAIN INHIBITORS | UNIV FREIBURG ALBERT LUDWIGS (DE) | 2024-06-26 | — | — | EP | disclosed |
| EP-3898587-B1 | CONDENSED PYRROLES AS NOVEL BROMODOMAIN INHIBITORS | UNIV FREIBURG ALBERT LUDWIGS (DE) | 2024-06-26 | — | — | EP | disclosed |
| US-20220055989-A1 | CONDENSED PYRROLES AS NOVEL BROMODOMAIN INHIBITORS | ALBERT LUDWING UNIV FREIBURG (DE) | 2022-02-24 | — | — | US | disclosed |
| US-20220055989-A1 | CONDENSED PYRROLES AS NOVEL BROMODOMAIN INHIBITORS | ALBERT LUDWING UNIV FREIBURG (DE) | 2022-02-24 | — | — | US | disclosed |
| WO-2020127846-A9 | CONDENSED PYRROLES AS NOVEL BROMODOMAIN INHIBITORS | ALBERT LUDWIG UNIVERSITÄT FREIBURG (DE) | 2021-08-12 | — | — | WO | disclosed |
| WO-2020127846-A1 | CONDENSED PYRROLES AS NOVEL BROMODOMAIN INHIBITORS | ALBERT LUDWIG UNIVERSITÄT FREIBURG (DE) | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220055989-A1 | CONDENSED PYRROLES AS NOVEL BROMODOMAIN INHIBITORS | BRD4, BRPF3, BRD2 | ALDH1A1 3347/4885MAPK1 1111/4885HPGD 813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.