Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.62 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.62 |
| ▸ | EP300 | Q09472 | 1/20 | 0.62 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | XBP1 | P17861 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | IGF1R | P08069 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22137286 | 0.84 | ALDH1A1 (0.55) | BRD4BRPF1EP300CREBBPALDH1A1 | |
| SCHEMBL22137275 | 0.83 | ALDH1A1 (0.54) | BRD4BRPF1EP300CREBBPALDH1A1 | |
| SCHEMBL1450411 | 0.83 | HPGD (0.80) | ALDH1A1MAPK1HPGDCYP1A2CYP2C9 | |
| SCHEMBL13919303 | 0.83 | IGF1R (0.61) | BRD4BRPF1EP300CREBBPALDH1A1 | |
| SCHEMBL4201730 | 0.82 | CYP1A2 (0.67) | BRD4ALDH1A1MAPK1HPGDCYP1A2 | |
| SCHEMBL27405249 | 0.81 | BRD4 (0.68) | BRD4BRPF1EP300CREBBPALDH1A1 | |
| SCHEMBL4205954 | 0.81 | CYP1A2 (0.76) | ALDH1A1MAPK1HPGDCYP1A2CYP2C9 | |
| SCHEMBL8911652 | 0.80 | CYP1A2 (0.44) | BRD4BRPF1EP300CREBBPALDH1A1 | |
| SCHEMBL2150867 | 0.79 | CYP1A2 (0.68) | ALDH1A1MAPK1HPGDCYP1A2CYP2C9 | |
| SCHEMBL16569542 | 0.79 | BRD4 (0.66) | BRD4BRPF1EP300CREBBPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6010805-A | Ion conducting electrolyte material containing a lithium porphyrin complex | UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2000-01-04 | — | — | US | disclosed |
| US-5679694-A | LOW TOXICITY AGAINST NORMAL CELL LINES | THE WELLCOME FOUNDATION LTD. (GB) | 1997-10-21 | — | — | US | disclosed |
| US-5464741-A | Palladium (II) octaethylporphine alpha-isothiocyanate as a phosphorescent label for immunoassays | HENWELL, INC. (US) | 1995-11-07 | — | — | US | disclosed |
| EP-0651750-A1 | TETRACYCLIC COMPOUNDS PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOUR AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1995-05-10 | — | — | EP | disclosed |
| WO-1994002483-A1 | TETRACYCLIC COMPOUNDS PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS ANTITUMOUR AGENTS | THE WELLCOME FOUNDATION LIMITED (GB) | 1994-02-03 | — | — | WO | disclosed |