Sugi Predict

Sugi Predict / Compounds / SCHEMBL22138185

SCHEMBL22138185

SCHEMBL22138185

c1ccc(-c2nc(-c3ccc4c(ccc5ccccc54)c3)nc(-c3ccc4oc5cc6ccccc6cc5c4c3)n2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 8/20 0.44
▸ ALDH1A1 P00352 8/20 0.44
▸ MAPT P10636 5/20 0.44
▸ HSD17B10 Q99714 4/20 0.44
▸ HPGD P15428 3/20 0.44
▸ TSHR P16473 2/20 0.44
▸ ALOX15 P16050 1/20 0.44
▸ CASP1 P29466 1/20 0.44
▸ CASP7 P55210 1/20 0.44
▸ GLA P06280 2/20 0.43
▸ HTT P42858 1/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ KMT2A Q03164 3/20 0.42
▸ MAPK1 P28482 1/20 0.42
▸ SMN1; SMN2 Q16637 2/20 0.41
▸ MEN1 O00255 2/20 0.41
▸ CYP1A2 P05177 2/20 0.41
▸ TP53 P04637 1/20 0.41
▸ GAA P10253 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24217172 0.93 KDM4E (0.47) KDM4EALDH1A1MAPTHSD17B10HPGD
SCHEMBL24215967 0.92 KDM4E (0.44) KDM4EALDH1A1MAPTHSD17B10HPGD
SCHEMBL24216922 0.92 KDM4E (0.44) KDM4EALDH1A1MAPTHSD17B10HPGD
SCHEMBL22138192 0.92 ALDH1A1 (0.49) KDM4EALDH1A1MAPTHSD17B10HPGD
SCHEMBL24473046 0.90 KDM4E (0.45) KDM4EALDH1A1MAPTHSD17B10HPGD
SCHEMBL25621650 0.90 KDM4E (0.45) KDM4EALDH1A1MAPTHSD17B10HPGD
SCHEMBL25460016 0.90 ALDH1A1 (0.39) KDM4EALDH1A1MAPTHSD17B10HPGD
SCHEMBL22138191 0.90 KMT2A (0.42) KDM4EALDH1A1MAPTHSD17B10HPGD
SCHEMBL22138493 0.90 KMT2A (0.42) KDM4EALDH1A1MAPTHSD17B10HPGD
SCHEMBL27370808 0.90 KDM4E (0.41) KDM4EALDH1A1MAPTHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11367839-B2 Compound for organic electric element, organic electric element using the same, and an electronic device thereof DUK SAN NEOLUX CO., LTD. (KR) 2022-06-21 — — US disclosed
US-20220029104-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2022-01-27 — — US disclosed
WO-2020130392-A1 COMPOUND FOR ORGANIC ELECTRIC ELEMENT, ORGANIC ELECTRIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING ORGANIC ELECTRIC ELEMENT 덕산네오룩스 주식회사 2020-06-25 — — WO disclosed
US-20200203623-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF DUK SAN NEOLUX CO., LTD. (KR) 2020-06-25 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11367839-B2 Compound for organic electric element, organic electric element using the same, and an electronic device thereof ORAI2, KCNJ2, OR10J3 KDM4E 410/4885ALDH1A1 2536/4885MAPT 3503/4885
US-20200203623-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING THE SAME, AND AN ELECTRONIC DEVICE THEREOF GPX1, PIEZO1, ORAI2 KDM4E 2039/4885ALDH1A1 1362/4885MAPT 3035/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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