SCHEMBL2213828

SCHEMBL2213828

N=C(N)Oc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2 P00734 2/20 0.46
F10 P00742 2/20 0.46
F12 P00748 1/20 0.46
F7 P08709 1/20 0.46
F3 P13726 1/20 0.46
PKM P14618 1/20 0.46
BLM P54132 1/20 0.44
PRSS1 P07477 3/20 0.42
PRSS2 P07478 2/20 0.42
C1S P09871 2/20 0.42
PRSS3 P35030 2/20 0.42
KMT2A Q03164 2/20 0.42
RECQL P46063 1/20 0.42
LTA4H P09960 1/20 0.41
TSHR P16473 1/20 0.41
PARP10 Q53GL7 2/20 0.41
ATM Q13315 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ACR P10323 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9505480 0.97 BLM (0.48) F2F10F12F7F3
Diphenyl Ethanedioat SCHEMBL2254079 0.78 PARP10 (0.46) F2F10F12F7F3
Guanidine SCHEMBL27886402 0.78 USP2 (0.49) PRSS1KMT2APARP10ATMTDP1
Guanidine SCHEMBL4786082 0.78 PARP10 (0.46) PRSS1KMT2APARP10ATMTDP1
SCHEMBL29287939 0.78 USP2 (0.45) PRSS1KMT2APARP10ATMTDP1
SCHEMBL2665439 0.78 LTA4H (0.45) F2F10F12F7F3
SCHEMBL9748729 0.78 LTA4H (0.45) F2F10F12F7F3
SCHEMBL19381846 0.77 PLAU (0.48) F2BLMPRSS1PRSS2PRSS3
SCHEMBL347473 0.76 LTA4H (0.43) F2F10F12F7F3
Diphenylether SCHEMBL28792708 0.76 LTA4H (0.67) F2F10F12F7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2026-03-12 US disclosed
EP-4186888-B1 COMPOUND AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2025-11-26 EP disclosed
US-20250228777-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2025-07-17 US disclosed
US-12324859-B2 Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2025-06-10 US disclosed
US-12263248-B2 Compounds and compositions for intracellular delivery of therapeutic agents MODERNATX, INC. (US) 2025-04-01 US disclosed
EP-4186888-A1 COMPOUND AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ModernaTX, Inc. (US) 2023-05-31 EP disclosed
US-20220409536-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS ARES CAPITAL CORPORATION, AS AGENT 2022-12-29 US disclosed
EP-3596041-B1 COMPOUND AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS MODERNATX INC (US) 2022-11-02 EP disclosed
CN-110551105-B Substituted triazoles useful as AXL inhibitors 里格尔制药公司 2022-10-18 CN disclosed
CN-114430775-A Quinoline inhibitors of RAD52 and methods of use 德雷克塞尔大学 2022-05-03 CN disclosed
US-6500824-B1 PSYCHOSIS, OR PARALYSIS DUE TO ISCHEMIC SPINAL CORD INJURY. REGENTS OF THE UNIVERSITY OF MINNESOTA 2002-12-31 US disclosed
US-6335352-B1 IL-8 receptor antagonists SMITHKLINE BEECHAM CORPORATION 2002-01-01 US disclosed
EP-0623604-B1 Oxa(Thia)-diazol-oxyphenylacrylates as pesticides BAYER AG (DE) 2001-08-08 EP disclosed
US-6204294-B1 GUANIDINE CONTAINING COMPOUNDS SMITHKLINE BEECHAM CORPORATION 2001-03-20 US disclosed
WO-2000008027-A1 KAPPA (OP2) OPIOID RECEPTOR ANTAGONISTS REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2000-02-17 WO disclosed
EP-0623604-A2 Oxa(Thia)-diazol-oxyphenylacrylates as pesticides BAYER AG (DE) 1994-11-09 EP disclosed
EP-0325336-B1 OXADIAZOLE COMPOUNDS, THEIR PREPARATION AND THEIR USE AS PESTICIDES SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1993-08-04 EP disclosed
US-4929628-A Oxadiazole compounds, their preparation and their use as pesticides SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ, B. V. (NL) 1990-05-29 US disclosed
EP-0325336-A1 Oxadiazole compounds, their preparation and their use as pesticides SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-07-26 EP disclosed
US-4225618-A FUNGICIDES, ARTHROPODICIDES BAYER AKTIENGESELLSCHAFT (DE) 1980-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12324859-B2 Compounds and compositions for intracellular delivery of therapeutic agents LNPK, PLTP, PLIN3 F2 4716/4885F10 4208/4885F12 2852/4885
US-12263248-B2 Compounds and compositions for intracellular delivery of therapeutic agents LNPK, PLTP, PLIN3 F2 4716/4885F10 4208/4885F12 2852/4885
US-20260069549-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS SIN3A, PLIN3, MSR1 F2 4766/4885F10 4418/4885F12 3882/4885
US-20220409536-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS LNPK, PLTP, PLIN3 F2 4716/4885F10 4208/4885F12 2852/4885
US-20250228777-A1 COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS LNPK, PLTP, PLIN3 F2 4716/4885F10 4208/4885F12 2852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.