SCHEMBL2213848

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL327188	0.93	DYRK1A (0.38)	DYRK1ADYRK2DYRK1BDYRK3LMNA
	SCHEMBL2212260	0.90	LMNA (0.40)	LMNAHTTMEN1KMT2ADGAT2
	SCHEMBL303432	0.89	LMNA (0.42)	LMNAHTTMEN1KMT2APOLB
	SCHEMBL303301	0.86	MEN1 (0.41)	LMNAHTTMEN1KMT2APOLB
	SCHEMBL2211916	0.86	MEN1 (0.42)	LMNAMEN1KMT2APOLBALDH1A1
	SCHEMBL304312	0.85	KMT2A (0.40)	LMNAMEN1KMT2APOLBALDH1A1
	SCHEMBL3377133	0.83	MEN1 (0.39)	LMNAMEN1KMT2ADGAT2POLB
	SCHEMBL2214180	0.83	MEN1 (0.54)	LMNAMEN1KMT2APOLBALDH1A1
	SCHEMBL2214837	0.82	MEN1 (0.44)	MEN1KMT2AALDH1A1
	SCHEMBL303882	0.82	KMT2A (0.40)	LMNAHTTMEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.