Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 9/20 | 0.34 |
| ▸ | MPEG1 | Q2M385 | 7/20 | 0.34 |
| ▸ | XIAP | P98170 | 5/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22139376 | 0.78 | HSP90AA1 (0.30) | — | |
| SCHEMBL22139358 | 0.76 | XIAP (0.39) | XIAPKDM4EMEN1ALDH1A1MAPT | |
| SCHEMBL22139362 | 0.72 | XIAP (0.34) | XIAPKDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL22139367 | 0.71 | ALOX5 (0.33) | ALOX5MPEG1XIAPGPR84KDM4E | |
| SCHEMBL22139360 | 0.69 | KDM4E (0.34) | XIAPKDM4EMEN1USP2ALDH1A1 | |
| SCHEMBL22139377 | 0.66 | NQO1 (0.36) | — | |
| SCHEMBL22139397 | 0.66 | XIAP (0.41) | XIAPKDM4EALDH1A1MAPTCYP2C9 | |
| SCHEMBL22139375 | 0.66 | PTGES (0.33) | ALOX5MEN1PTGESHPGDKMT2A | |
| SCHEMBL22139370 | 0.64 | HPGD (0.46) | ALOX5KDM4EALDH1A1CYP2D6HPGD | |
| SCHEMBL22139365 | 0.62 | PTGES (0.35) | ALOX5KDM4EMEN1PTGESALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200199058-A1 | SQUARYLIUM COMPOUNDS FOR USE IN DISPLAY DEVICES | NITTO DENKO CORPORATION (JP) | 2020-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200199058-A1 | SQUARYLIUM COMPOUNDS FOR USE IN DISPLAY DEVICES | SQLE, FDFT1, ALDH1A2 | ALOX5 1459/4885MPEG1 1728/4885XIAP 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.