SCHEMBL22140282

SCHEMBL22140282

CCCC(C)(CC)c1cccnc1Br

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.33
TRIM33 Q9UPN9 1/20 0.33
AR P10275 1/20 0.31
TLR8 Q9NR97 1/20 0.31
CYP11B1 P15538 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22140286 0.81 P2RX7 (0.33) TLR8
SCHEMBL22140323 0.80 TDP1 (0.37) TLR8
SCHEMBL22140273 0.80 KCNA5 (0.33) TLR8
SCHEMBL22140204 0.80 JAK3 (0.31) TLR8
SCHEMBL19176444 0.78 PLCG1 (0.35)
SCHEMBL19176512 0.76 KDM4E (0.30)
SCHEMBL23419232 0.74 SSTR4 (0.41)
SCHEMBL2608421 0.74 TRIM24 (0.42) TRIM24TRIM33CYP11B1CYP11B2
SCHEMBL20857327 0.73 TLR8 (0.39) TLR8
SCHEMBL15372342 0.73 KDM4E (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11000038-B2 Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients MITSUI CHEMICALS AGRO, INC. (JP) 2021-05-11 US disclosed
US-20200196600-A1 PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS MITSUI CHEMICALS AGRO, INC. (JP) 2020-06-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200196600-A1 PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS PNPO, PDXK, PLPBP TRIM24 2583/4885TRIM33 2437/4885AR 2582/4885
US-11000038-B2 Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients PNPO, PDXK, PLPBP TRIM24 2583/4885TRIM33 2437/4885AR 2582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.