Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR2C | P28335 | 7/20 | 0.36 |
| ▸ | HTR2B | P41595 | 6/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11772985 | 0.76 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3HTR1AHTR2C | |
| SCHEMBL10935160 | 0.68 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3HTR1AHTR2C | |
| SCHEMBL30786039 | 0.67 | MEN1 (0.38) | HTR2CHTR2BHTR2ATAAR1SLC18A3 | |
| SCHEMBL2214066 | 0.66 | HTR2C (0.42) | SLC6A2SLC6A4SLC6A3HTR1AHTR2C | |
| SCHEMBL8611203 | 0.63 | LTA4H (0.52) | SLC6A2SLC6A4SLC6A3HTR1AHTR2A | |
| SCHEMBL3886540 | 0.62 | ADRA2A (0.39) | HTR2CHTR2BHTR2ASLC18A3SIGMAR1 | |
| SCHEMBL3887869 | 0.62 | BPTF (0.45) | SLC6A4HTR2CHTR2BHTR2A | |
| SCHEMBL3886031 | 0.62 | BPTF (0.45) | SLC6A4HTR2CHTR2BHTR2A | |
| SCHEMBL3886029 | 0.62 | BPTF (0.45) | SLC6A4HTR2CHTR2BHTR2A | |
| SCHEMBL3886033 | 0.62 | BPTF (0.45) | SLC6A4HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342178-A1 | SUBSTITUTED AMINOINDANES AND ANALOGS THEREOF, AND THE PHARMACEUTICAL USE THEREOF | Sanofi-Aventis (FR) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010025856-A1 | SUBSTITUTED AMINOINDANES AND ANALOGS THEREOF, AND THE PHARMACEUTICAL USE THEREOF | SANOFI-AVENTIS (FR) | 2010-03-11 | — | — | WO | disclosed |