Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 12/20 | 0.42 |
| ▸ | HTR2B | P41595 | 10/20 | 0.42 |
| ▸ | HTR2A | P28223 | 8/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15974677 | 0.73 | SLC6A2 (0.51) | HTR2CHTR2BHTR2AHRH1HTR1A | |
| Hydrochloric Acid SCHEMBL7932246 | 0.71 | HRH1 (0.44) | HTR2CHTR2BHRH1HTR1ASLC6A2 | |
| SCHEMBL27889106 | 0.71 | HRH1 (0.40) | HTR2CHTR2BHRH1HTR1ASLC6A2 | |
| Hydrochloric Acid SCHEMBL7932341 | 0.69 | HRH1 (0.36) | HTR2CHTR2BHRH1HTR1ASLC6A2 | |
| SCHEMBL9286439 | 0.68 | PRCP (0.37) | HTR2CHTR2BHRH1HTR1ASLC6A2 | |
| SCHEMBL3874553 | 0.66 | HTR2C (0.51) | HTR2CHTR2BHTR2ATAAR1 | |
| SCHEMBL2214065 | 0.66 | SLC6A2 (0.36) | HTR2CHTR2BHTR2AHRH1HTR1A | |
| SCHEMBL6692817 | 0.66 | HTR2C (0.45) | HTR2CHTR2BHTR2ATAAR1GRIN2B | |
| SCHEMBL6646375 | 0.66 | GRIN2B (0.55) | HTR2CHTR2BHTR2AHTR1ATAAR1 | |
| Hydrochloric Acid SCHEMBL2224880 | 0.64 | HPGD (0.54) | HTR2CHTR2BHTR2AHTR1ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2342178-A1 | SUBSTITUTED AMINOINDANES AND ANALOGS THEREOF, AND THE PHARMACEUTICAL USE THEREOF | Sanofi-Aventis (FR) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010025856-A1 | SUBSTITUTED AMINOINDANES AND ANALOGS THEREOF, AND THE PHARMACEUTICAL USE THEREOF | SANOFI-AVENTIS (FR) | 2010-03-11 | — | — | WO | disclosed |