SCHEMBL8022993

SCHEMBL8022993

Cc1cc[n+](CCC(=O)O)c2ccccc12

nearest known ligand 0.97

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.97
POLB P06746 1/20 0.97
RECQL P46063 1/20 0.61
MAPT P10636 3/20 0.49
HTT P42858 2/20 0.49
KMT2A Q03164 2/20 0.49
TSHR P16473 2/20 0.49
CYP2D6 P10635 1/20 0.49
HSD17B10 Q99714 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.45
LMNA P02545 1/20 0.41
RAB9A P51151 2/20 0.40
MEN1 O00255 1/20 0.40
NPC1 O15118 1/20 0.38
ALDH1A1 P00352 1/20 0.38
PRNP P04156 1/20 0.38
MAPK10 P53779 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodide SCHEMBL29210094 0.98 KDM4E (0.94) KDM4EPOLBRECQLMAPTHTT
Bromide SCHEMBL8512189 0.98 KDM4E (1.00) KDM4EPOLBRECQLMAPTHTT
SCHEMBL16663887 0.91 KDM4E (0.81) KDM4EPOLBRECQLMAPTHTT
SCHEMBL15419914 0.90 KDM4E (0.79) KDM4EPOLBRECQLMAPTHTT
SCHEMBL1105809 0.88 KDM4E (0.77) KDM4EPOLBRECQLMAPTHTT
Bromide SCHEMBL3915979 0.87 KDM4E (0.80) KDM4EPOLBRECQLMAPTHTT
Iodide SCHEMBL2057098 0.87 KDM4E (0.75) KDM4EPOLBRECQLMAPTHTT
SCHEMBL8512187 0.86 KDM4E (0.74) KDM4EPOLBRECQLMAPTHTT
Butyric Acid SCHEMBL1362446 0.85 KDM4E (0.72) KDM4EPOLBRECQLMAPTHTT
SCHEMBL5020848 0.84 RECQL (0.73) KDM4EPOLBRECQLMAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160155575-A1 METHINE DYES WITH LARGE ORGANIC COUNTER ANION FOR DYE SENSITIZED SOLAR CELLS BASF SE (DE) 2016-06-02 US disclosed
US-20150076420-A1 Dye-Sensitized Photoelectric Conversion Element NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2015-03-19 US disclosed
US-8735720-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2014-05-27 US disclosed
US-8227690-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-07-24 US disclosed
US-8227690-B2 Dye-sensitized photoelectric conversion device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2012-07-24 US disclosed
US-8022293-B2 Using oxide semiconductor particles sensitized with an N,N,N*,N*-tetraphenyl-p-phenylenediamine derivative methine dye; solar cells with high stability and conversion efficiency NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-09-20 US disclosed
US-8022293-B2 Using oxide semiconductor particles sensitized with an N,N,N*,N*-tetraphenyl-p-phenylenediamine derivative methine dye; solar cells with high stability and conversion efficiency NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2011-09-20 US disclosed
US-20090044857-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-02-19 US disclosed
US-20090044857-A1 Dye-Sensitized Photoelectric Conversion Device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2009-02-19 US disclosed
US-20080067476-A1 Dye-Sensitized Photoelectic Conversion Devices NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-03-20 US disclosed
US-20080067476-A1 Dye-Sensitized Photoelectic Conversion Devices NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2008-03-20 US disclosed
EP-0710668-B1 Covalent attachment of thiazole orange to oligonucleotides for use in nucleic acid detection BECTON DICKINSON CO (US) 2000-02-16 EP disclosed
US-5650275-A Target detection method using spectroscopically detectable nucleic acid ligands GILEAD SCIENCES, INC. 1997-07-22 US disclosed
US-5641629-A MEASURING FLUORESCENCE POLARIZATION, ANISOTROPY VALUES OR ROTATIONAL CORRELATION TIMES OF LABELED NUCLEIC ACID LIGAND, ADDING TO SAMPLE, DETERMINING DIFFERENCE IN MEASURED VALUES TO INDICATE PRESENCE OF TARGET COMPOUND GILEAD SCIENCES, INC. 1997-06-24 US disclosed
US-5597696-A FLUORESCENCE BECTON DICKINSON AND COMPANY (US) 1997-01-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090044857-A1 Dye-Sensitized Photoelectric Conversion Device CRY1, H1-5, CHRM1 KDM4E 384/4885POLB 2159/4885RECQL 211/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.