Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1199570 | 1.00 | TSHR (0.47) | TSHRCA1CA2CA12CA4 | |
| SCHEMBL1200418 | 0.85 | GAA (0.55) | SMN1; SMN2HPGDALDH1A1SGMS2POLB | |
| SCHEMBL1200542 | 0.83 | CTDSP1 (0.46) | TSHRKDM4EMAPTALOX15HSD17B10 | |
| SCHEMBL1200820 | 0.83 | TSHR (0.42) | TSHRCA1CA2CA7CA9 | |
| SCHEMBL7868993 | 0.82 | KDM4E (0.37) | TSHRCA1CA2CA12CA4 | |
| SCHEMBL1200839 | 0.82 | TSHR (0.41) | TSHRKDM4ESMN1; SMN2MAPTHPGD | |
| SCHEMBL1199595 | 0.82 | PTGS2 (0.47) | TSHRKDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL1200939 | 0.80 | AR (0.44) | TSHRKDM4ESMN1; SMN2MAPTHPGD | |
| Benzene SCHEMBL1200605 | 0.80 | PTGS2 (0.50) | TSHRKDM4EMAPTHPGDALOX15 | |
| SCHEMBL13937393 | 0.80 | TSHR (0.61) | TSHRKDM4EMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4273132-A2 | PROCESSES FOR PREPARING ACC INHIBITORS AND SOLID FORMS THEREOF | Gilead Sciences, Inc. (US) | 2023-11-08 | — | — | EP | disclosed |
| EP-3589636-B1 | PROCESSES FOR PREPARING ACC INHIBITORS AND SOLID FORMS THEREOF | GILEAD SCIENCES INC (US) | 2023-09-13 | — | — | EP | disclosed |
| US-20210024537-A1 | PROCESSES FOR PREPARING ACC INHIBITORS AND SOLID FORMS THEREOF | GILEAD SCIENCES, INC. | 2021-01-28 | — | — | US | disclosed |
| US-10745412-B2 | Processes for preparing ACC inhibitors and solid forms thereof | GILEAD SCIENCES, INC. (US) | 2020-08-18 | — | — | US | disclosed |
| US-20200199147-A1 | PROCESSES FOR PREPARING ACC INHIBITORS AND SOLID FORMS THEREOF | GILEAD SCIENCES, INC. | 2020-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210024537-A1 | PROCESSES FOR PREPARING ACC INHIBITORS AND SOLID FORMS THEREOF | ACACA, ACACB, ACAT2 | TSHR 4377/4885CA1 1233/4885CA2 1306/4885 |
| US-10745412-B2 | Processes for preparing ACC inhibitors and solid forms thereof | ACACA, ACACB, ACAT2 | TSHR 4377/4885CA1 1233/4885CA2 1306/4885 |
| US-20200199147-A1 | PROCESSES FOR PREPARING ACC INHIBITORS AND SOLID FORMS THEREOF | ACACA, ACACB, ACAT2 | TSHR 4377/4885CA1 1233/4885CA2 1306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.