Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP15 | Q460N3 | 4/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11792919 | 0.82 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2LMNAHTTPKM | |
| SCHEMBL6552462 | 0.79 | LMNA (0.61) | ALDH1A1SMN1; SMN2LMNAHTTPKM | |
| SCHEMBL5853216 | 0.77 | HPGD (0.53) | PARP15PARP10PARP2ALDH1A1SMN1; SMN2 | |
| SCHEMBL12445261 | 0.76 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2AKR1C3KDM1AHPGD | |
| SCHEMBL11142367 | 0.76 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2AKR1C3HPGDNPC1 | |
| SCHEMBL11113445 | 0.75 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2LMNAHTTPKM | |
| SCHEMBL17946119 | 0.75 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2LMNAHTTPKM | |
| SCHEMBL20000540 | 0.75 | PARP15 (0.51) | PARP15PARP10PARP2ALDH1A1HRH3 | |
| SCHEMBL22065525 | 0.75 | KDM1A (0.62) | ALDH1A1SMN1; SMN2LMNAHTTPKM | |
| SCHEMBL1776266 | 0.74 | KDM1A (0.59) | ALDH1A1SMN1; SMN2LMNAHTTPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132561-A1 | TARGETED PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |