Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 4/20 | 0.33 |
| ▸ | RXRB | P28702 | 2/20 | 0.33 |
| ▸ | RXRG | P48443 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.33 |
| ▸ | RARB | P10826 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | RARG | P13631 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14538523 | 0.78 | ALDH1A1 (0.40) | MEN1KMT2AMAPTSMN1; SMN2HDAC1 | |
| SCHEMBL13439334 | 0.73 | NQO2 (0.38) | RXRARXRBMEN1KMT2AMAPT | |
| SCHEMBL21371239 | 0.73 | IRAK4 (0.35) | IRAK4PRSS1PRSS2PRSS3 | |
| SCHEMBL26414498 | 0.71 | TAS1R3 (0.38) | MEN1KMT2ARAB9APRSS1PRSS2 | |
| SCHEMBL24711679 | 0.68 | PARP1 (0.48) | MEN1KMT2AKCNH2NPC1SMN1; SMN2 | |
| SCHEMBL16105803 | 0.66 | NPSR1 (0.45) | RXRARXRBRXRGMEN1CYP26A1 | |
| SCHEMBL20712737 | 0.66 | PRSS1 (0.33) | IRAK4PRSS1PRSS2PRSS3 | |
| SCHEMBL16105416 | 0.66 | AKR1C3 (0.44) | MEN1KMT2ANPC1SMN1; SMN2HPGD | |
| SCHEMBL23654930 | 0.65 | MEN1 (0.36) | MEN1ADRA2AKMT2ASMN1; SMN2 | |
| SCHEMBL21371129 | 0.65 | ESR2 (0.47) | RARBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020132561-A1 | TARGETED PROTEIN DEGRADATION | C4 THERAPEUTICS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |