Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | TPMT | P51580 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.35 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26016906 | 0.81 | TAS1R3 (0.39) | TAS1R3TAS1R1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL26017041 | 0.76 | LMNA (0.34) | MAOBMEN1RAB9AKMT2APDE4A | |
| SCHEMBL21371239 | 0.75 | IRAK4 (0.35) | PRSS1PRSS2PRSS3 | |
| SCHEMBL27441076 | 0.75 | PRSS1 (0.62) | CYP1A2CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL18685203 | 0.74 | CA12 (0.53) | TSHRCA12CA1CA2CA4 | |
| SCHEMBL25721432 | 0.73 | PRSS1 (0.57) | CYP3A4PRSS1MAOBMEN1RAB9A | |
| SCHEMBL16953406 | 0.72 | TSHR (0.45) | TAS1R3TAS1R1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL14538523 | 0.72 | ALDH1A1 (0.40) | MEN1KMT2AALDH1A1LMNAHTT | |
| SCHEMBL22241297 | 0.72 | ACHE (0.44) | CYP3A4CYP2C9CYP2C19MEN1RAB9A | |
| SCHEMBL3340955 | 0.72 | MAPK1 (0.60) | TAS1R3TAS1R1CYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023072962-A1 | SUBSTITUTED QUINOLINES AS IMPROVED NF-KB-INDUCING KINASE (NIK) INHIBITORS | Yukin Therapeutics (FR) | 2023-05-04 | — | — | WO | disclosed |
| EP-4169904-A1 | SUBSTITUTED QUINOLINES AS IMPROVED NF-KB-INDUCING KINASE (NIK) INHIBITORS | Yukin Therapeutics (FR) | 2023-04-26 | — | — | EP | disclosed |