Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.32 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2214528 | 0.88 | LMNA (0.36) | LMNAHSD17B10ALDH1A1KDM4CCYP2D6 | |
| SCHEMBL6730282 | 0.84 | ALDH1A1 (0.38) | LMNAHSD17B10ALDH1A1KDM4CCYP2D6 | |
| SCHEMBL6730280 | 0.78 | KDM4C (0.37) | LMNAHSD17B10ALDH1A1KDM4CCYP2D6 | |
| SCHEMBL23770097 | 0.77 | LMNA (0.41) | LMNAHSD17B10ALDH1A1KDM4CTSHR | |
| SCHEMBL21813306 | 0.76 | CYP2D6 (0.37) | CYP2D6CYP2C19 | |
| SCHEMBL10900663 | 0.74 | CYP2D6 (0.36) | CYP2D6CYP2C19 | |
| SCHEMBL10426442 | 0.74 | ALDH1A1 (0.35) | ALDH1A1KDM4CEPHX1 | |
| SCHEMBL1934610 | 0.72 | — | — | |
| SCHEMBL6729276 | 0.71 | SMN1; SMN2 (0.38) | LMNAHSD17B10ALDH1A1KDM4CCYP2D6 | |
| SCHEMBL23173503 | 0.71 | TDP1 (0.44) | LMNAHSD17B10ALDH1A1TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3446681-B1 | ABUSE RESISTANT CAPSULE | SCHERER TECHNOLOGIES LLC R P (US) | 2020-12-23 | — | — | EP | claimed |
| EP-2968129-B1 | ABUSE RESISTANT CAPSULE | SCHERER TECHNOLOGIES LLC R P (US) | 2018-09-05 | — | — | EP | claimed |
| EP-1558257-B1 | DOSAGE FORM THAT IS SAFEGUARDED FROM ABUSE | GRUENENTHAL GMBH (DE) | 2013-12-25 | — | — | EP | claimed |
| EP-1515702-B1 | ABUSE-PROTECTED ADMINISTRATION FORM | GRUENENTHAL GMBH (DE) | 2008-10-15 | — | — | EP | claimed |
| EP-1558221-B1 | DOSAGE FORM THAT IS SAFEGUARDED FROM ABUSE | GRUENENTHAL GMBH (DE) | 2007-06-06 | — | — | EP | claimed |
| EP-1558257-A1 | DOSAGE FORM THAT IS SAFEGUARDED FROM ABUSE | Grünenthal GmbH (DE) | 2005-08-03 | — | — | EP | claimed |
| EP-1558221-A1 | DOSAGE FORM THAT IS SAFEGUARDED FROM ABUSE | Grünenthal GmbH (DE) | 2005-08-03 | — | — | EP | claimed |
| EP-1515702-A1 | ABUSE-PROTECTED ADMINISTRATION FORM | Grünenthal GmbH (DE) | 2005-03-23 | — | — | EP | claimed |
| WO-2004037230-A1 | DOSAGE FORM THAT IS SAFEGUARDED FROM ABUSE | Grünenthal GmbH (DE) | 2004-05-06 | — | — | WO | claimed |
| WO-2004037259-A1 | DOSAGE FORM THAT IS SAFEGUARDED FROM ABUSE | Grünenthal GmbH (DE) | 2004-05-06 | — | — | WO | claimed |
| WO-2003105808-A1 | ABUSE-PROTECTED ADMINISTRATION FORM | Grünenthal GmbH (DE) | 2003-12-24 | — | — | WO | claimed |
| EP-1765303-B2 | ORAL TABLET SAFEGUARDED AGAINST ABUSE | GRUENENTHAL GMBH (DE) | 2022-11-23 | — | — | EP | disclosed |
| EP-2131830-B1 | PHARMACEUTICAL FORM WITH IMPEDED ABUSE | GRUENENTHAL GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| EP-1859789-B1 | Dosage form that is secured against misuse | GRUENENTHAL GMBH (DE) | 2016-02-17 | — | — | EP | disclosed |
| EP-1845955-B1 | METHOD FOR THE PRODUCTION OF A TAMPER-PROOF FORM OF ADMINISTRATION | GRUENENTHAL GMBH (DE) | 2015-05-27 | — | — | EP | disclosed |
| WO-2004037230-A1 | DOSAGE FORM THAT IS SAFEGUARDED FROM ABUSE | Grünenthal GmbH (DE) | 2004-05-06 | — | — | WO | disclosed |
| EP-0595364-B1 | Benz[e]indene derivatives and a process for preparing them as well as medicaments containing them and the use of them | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1996-07-24 | — | — | EP | disclosed |
| EP-0619299-A2 | 1-(Phenyl)-3-[omega-(amino)-alkoxyimino]-alk-1-ene derivatives, a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-10-12 | — | — | EP | disclosed |
| EP-0595364-A1 | Benz[e]indene derivatives and a process for preparing them as well as medicaments containing them and the use of them | EGIS GYOGYSZERGYAR RT. (HU) | 1994-05-04 | — | — | EP | disclosed |
| EP-0014263-A2 | Method of improving the solubility of biologically active agents in water and in lower aliphatic alcohols, and compounds having an improved solubility | BAYER AG (DE) | 1980-08-20 | — | — | EP | disclosed |