Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB4 | P54760 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PRKCZ | Q05513 | 3/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18965126 | 0.90 | EPHB4 (0.49) | EPHB4LMNAPKM | |
| SCHEMBL22146385 | 0.90 | LMNA (0.43) | EPHB4LMNAPKMNPSR1POLB | |
| SCHEMBL22146193 | 0.90 | EPHB4 (0.39) | EPHB4LMNAPKMNPSR1GRM2 | |
| SCHEMBL22146189 | 0.87 | NOTUM (0.36) | EPHB4LMNAPKMCYP1A2 | |
| SCHEMBL22146201 | 0.85 | PKM (0.45) | EPHB4LMNAPRKCZPKMPIK3CD | |
| SCHEMBL22146209 | 0.84 | NPSR1 (0.34) | EPHB4LMNAPKMNPSR1GRM2 | |
| SCHEMBL22146195 | 0.82 | EPHB4 (0.37) | EPHB4LMNAPKMNPSR1GRM2 | |
| SCHEMBL22146197 | 0.81 | LMNA (0.43) | EPHB4LMNAPKMNPSR1POLB | |
| SCHEMBL22146154 | 0.79 | TRPA1 (0.36) | EPHB4LMNAPKM | |
| SCHEMBL22146148 | 0.78 | LMNA (0.41) | LMNAPKMNPSR1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3386591-B1 | HETEROAROMATIC NMDA RECEPTOR MODULATORS AND USES THEREOF | CADENT THERAPEUTICS INC (US) | 2020-06-24 | — | — | EP | disclosed |