Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.34 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | COMT | P21964 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12618996 | 0.81 | KDM4E (0.39) | KDM4EALDH1A1GLAGAAAKT1 | |
| SCHEMBL12750259 | 0.79 | ALDH1A1 (0.53) | KDM4EALDH1A1GAACOMT | |
| SCHEMBL22167597 | 0.75 | ALDH1A1 (0.35) | KDM4EALDH1A1COMT | |
| SCHEMBL22152284 | 0.74 | ADORA3 (0.38) | KDM4EALDH1A1AKT1AKT2GPR139 | |
| SCHEMBL22146342 | 0.74 | TLR9 (0.38) | KDM4EALDH1A1COMT | |
| SCHEMBL22152347 | 0.74 | HTR6 (0.37) | KDM4EALDH1A1AKT1AKT2COMT | |
| SCHEMBL17541168 | 0.73 | AKT1 (0.34) | KDM4EALDH1A1GLAGAAAKT1 | |
| SCHEMBL22146349 | 0.73 | USP7 (0.43) | KDM4EALDH1A1 | |
| SCHEMBL22145959 | 0.72 | TDP1 (0.41) | KDM4EALDH1A1GAAAKT1AKT2 | |
| SCHEMBL23103297 | 0.71 | PRMT5 (0.39) | KDM4EALDH1A1GLAGAAAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020124397-A1 | C-TERMINAL SRC KINASE INHIBITORS | INVENTISBIO SHANGHAI LTD. (CN) | 2020-06-25 | — | — | WO | disclosed |
| WO-2020125615-A1 | C-TERMINAL SRC KINASE INHIBITORS | INVENTISBIO SHANGHAI LTD. (CN) | 2020-06-25 | — | — | WO | disclosed |