SCHEMBL2214657

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL13313203	0.83	KMT2A (0.54)	PDE10AAURKAAURKBTNKSTNKS2
	SCHEMBL2836126	0.82	TDO2 (0.46)	AURKAAURKBKMT2ALMNAMEN1
	SCHEMBL13313215	0.79	PARP1 (0.50)	TNKSTNKS2KMT2ALMNAMEN1
	SCHEMBL15857826	0.79	KDM4E (0.45)	PDE10ATNKSTNKS2PARP2KMT2A
	SCHEMBL8073660	0.77	KDM4E (0.44)	KMT2ALMNAMEN1ABCG2KDM4E
	SCHEMBL15268291	0.76	KDM4E (0.49)	PDE10ATNKSTNKS2PARP2KMT2A
	SCHEMBL30428808	0.76	ADORA2A (0.50)	KDM4EALDH1A1HPGD
	SCHEMBL22805746	0.76	ADORA2A (0.50)	KDM4EALDH1A1HPGD
	SCHEMBL2838426	0.75	WHR1 (0.58)	KMT2ALMNAMEN1ABCG2KDM4E
	SCHEMBL28568819	0.75	DHPS (0.59)	KMT2AMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.