Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ARG1 | P05089 | 1/20 | 0.76 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | TYMP | P19971 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21062468 | 0.87 | ARG1 (1.00) | ARG1TLR8KMT2ASMN1; SMN2TSHR | |
| SCHEMBL20539253 | 0.87 | ARG1 (1.00) | ARG1TLR8KMT2ASMN1; SMN2TSHR | |
| SCHEMBL20539252 | 0.87 | ARG1 (1.00) | ARG1TLR8KMT2ASMN1; SMN2TSHR | |
| SCHEMBL22923264 | 0.86 | ARG1 (0.72) | ARG1TLR8ALDH1A1KMT2APOLB | |
| SCHEMBL25471583 | 0.85 | ARG1 (0.71) | ARG1TLR8ALDH1A1KMT2APOLB | |
| SCHEMBL25471582 | 0.81 | ARG1 (0.66) | ARG1TLR8ALDH1A1KMT2APOLB | |
| Trifluoroacetic Acid SCHEMBL30759415 | 0.80 | ARG1 (0.85) | ARG1TLR8KMT2ASMN1; SMN2KCNH2 | |
| SCHEMBL25469172 | 0.79 | ARG1 (0.72) | ARG1TLR8ALDH1A1KMT2APOLB | |
| SCHEMBL7373337 | 0.78 | ARG1 (0.64) | ARG1TLR8ALDH1A1KCNH2 | |
| SCHEMBL31250497 | 0.77 | ARG1 (0.56) | ARG1TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11795196-B2 | Mitochondria-targeting peptides | STEALTH BIOTHERAPEUTICS INC. (US) | 2023-10-24 | — | — | US | disclosed |
| WO-2020131283-A1 | ANALOGS THAT TARGET MITOCHONDRIAL DISEASES | STEALTH BIOTHERAPEUTICS CORP. (MC) | 2020-06-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11795196-B2 | Mitochondria-targeting peptides | HSPE1, TFAM, TNNI3 | ARG1 576/4885TLR8 2713/4885ALDH1A1 3737/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.